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The dancing amino acids of ubiquitin

By 28 de June de 2011November 18th, 2020No Comments
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 28.06.2011

The dancing amino acids of ubiquitin

Through a successful combination of NMR experiments and computational modelling, scientists led by ICREA researcher Xavier Salvatella, with the Joint Programme on Computational Biology between IRB Barcelona –based at the Barcelona Scientific Park– and the Barcelona Supercomputing Centre, and Professor Christian Griesinger at the Max Planck Institute for Biophysical Chemistry, have followed the movements of the 76 amino acids of the model protein ubiquitin. The study, published in the Journal of the American Chemical Society (JACS), demonstrates the existence of weak long-range motions correlated between distal residues within the protein-binding interface.

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