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Beating the regeneration blockers

By 17 de November de 2010November 18th, 2020No Comments
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 17.11.2010

Beating the regeneration blockers

It's known that the development of neuronal diseases such as multiple sclerosis and Alzheimer's disease is connected with the levels of myelin – an insulating substance around nerve fibres – in the body, although the actual causes of these conditions remain unknown. Now researchers at IBEC have discovered a new group of interacting partners for myelin-associated receptors, which could shed light on the significance of imbalanced production or modifications of the substance.

In a study published online by the journal The FASEB Journal () this week, group leader José Antonio del Río, together with his postdocs Vanessa Gil and Franc Llorens, have been looking at axons, ligands and receptors in the mammalian central nervous system. Following injury in adults, axons have a limited capacity for regrowth; this restriction is caused by myelin-associated inhibitors (MAIs).