Esdeveniments

Carregant Esdeveniments

« Tots els Esdeveniments

  • Aquest esdeveniment ja ha passat.

2 desembre 2022 @ 12:00 - 14:00

New tricks of an old player: senescence induced-cellular plasticity in tissue regeneration and degeneration

Speaker: Dr. Han Li – Group Leader – Cellular plasticity in age-related pathologies  (Department of Development and Stem Cell Biology) – Institut Pasteur, Paris, France.

Cellular senescence is a form of stress response to various stimuli that leads to stable cell-cycle arrest, which plays a crucial role in tumor suppression and negatively impacts healthy aging. Recent studies have expanded their roles in embryonic development and tissue regeneration.

Cellular plasticity is the capacity of a cell to adopt different identities in response to environmental stimuli. Cellular reprogramming to pluripotency is the best example of how plastic a terminally differentiated cell can have, which has tremendous implications in tissue regeneration and tumorigenesis. Although it is increasingly recognized that adult somatic cells can acquire plasticity under both physiological and pathological conditions, the mechanisms underlying cell fate conversion are mostly unknown.

She will discuss the impact of cellular senescence on cellular plasticity in the context of reprogramming and tissue regeneration, with a particular focus on the heterogeneity of the senescence phenotype.

Mostra els detalls

Data:
2 desembre 2022
Hora:
12:00 - 14:00
Categoria d'Esdeveniment:
Lloc web:
https://www.irbbarcelona.org/ca/events/new-tricks-old-player-senescence-induced-cellular-plasticity-tissue-regeneration-and

Organitzador

IRB Barcelona – Institut de Recerca Biomedica
Visualitza el lloc web de Organitzador

Recinte

Edifici Torres R+D+I, Auditori Antoni Caparrós
C/ Baldiri Reixac 4-8
Barcelona, Barcelona 08028 Espanya
+ Mapa de Google
Telèfon
934034509
Visualitza el lloc web de Recinte