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març 27 @ 12:00 - 13:30

How to develop amino acid transporter inhibitors (the good, the bad and the ugly)?

Speaker: Professor Stefan Bröer, Research School of Biology,Australian National University, Canberra, Australia.

Abstract

Amino acid transporters have developed into drugs targets for metabolic diseases, orphan diseases and cancer. This talk will present experiences with a variety of amino acid transport inhibitors. It will focus on methods to develop and validate amino acid transport inhibitors and possible pitfalls in lead compound development. This includes a variety of transport assays, structural and computational data.

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