UB scientists identify key mechanistic aspects of the enzymes that trim carbohydrates attached to proteins Blog Post

Researchers from the Quantum Simulation of Biological Processes Research Group (), Department of Chemistry, University of Barcelona (UB) – located at the Barcelona Science Park (PCB) – in collaboration with biochemical and structural biology groups from the UK, France and Australia, have identified important mechanistic aspects of of the enzymes that trim carbohydrates attached to proteins. The study has been published in the current issue of Angewandte Chemie (), and has been classified as a VIP (“Very Important Paper”). Only 5% of papers published in Angew. Chem. receive this distinction.

Albert Ardèvol wins the ‘SusChem Young Chemical Researchers’ Blog Post

Albert-Ardèvol, who carried out his PhD in the Computational Modeling and Simulation Laboratory () at the Barcelona Science Park, just won the ‘‘ in the category PREDOC category for his study ‘The molecular mechanism of enzymatic glycosyl transfer with retention of configuration: evidence for a short-lived oxocarbenium ion-like species‘, published in 2011 in Angewandte Chemie (), one of the most prestigious journals in chemistry.

Deciphering the mechanism of glycosidic bond formation Blog Post

Using quantum molecular simulation techniques, researchers at the group of Quantum Simulation of Biological Processes (SQPBIO) of the Computer Simulation and Modelling Laboratory (Co.S.Mo.LAB) –located at the Barcelona Science Park (PCB)- have cracked the mechanism of glycosidic bond formation in glycosyltransferases, the enzymes responsible for the structure of many carbohydrates. The study appears this week in the Angewandte Chemie (doi:10.1002/anie.201104623) and it has been classified as VIP («Very Important Paper»).