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X-WR-CALNAME:Parc Científic de Barcelona
X-ORIGINAL-URL:https://www.pcb.ub.edu
X-WR-CALDESC:Esdeveniments per Parc Científic de Barcelona
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BEGIN:VTIMEZONE
TZID:Europe/Madrid
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20210328T010000
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DTSTART:20211031T010000
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DTSTART:20221030T010000
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DTSTART:20230326T010000
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DTSTART:20231029T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221003T080000
DTEND;TZID=Europe/Madrid:20221003T090000
DTSTAMP:20220915T112545Z
CREATED:20220915T112529Z
LAST-MODIFIED:20220915T112545Z
UID:76984-1664784000-1664787600@www.pcb.ub.edu
SUMMARY:Inscripcions obertes a les classes de ioga 2022-2023
DESCRIPTION:El dilluns 3 d’octubre es reprenen les classes de ioga de la mà de la Sílvia Delgado. \nConsulteu tota la informació al T’interessa
URL:https://www.pcb.ub.edu/esdeveniment/inscripcions-obertes-a-les-classes-de-ioga-2022-2023/
LOCATION:Edifici Cluster II\, Sala Dolors Aleu\, Avinguda Dr. Marañón 6-8\, Barcelona\, Barcelona\, 08028
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/09/ioa-petit.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221005T100000
DTEND;TZID=Europe/Madrid:20221005T120000
DTSTAMP:20221004T111550Z
CREATED:20221004T111539Z
LAST-MODIFIED:20221004T111550Z
UID:77541-1664964000-1664971200@www.pcb.ub.edu
SUMMARY:Differential migration mechanics and immune response of glioblastoma subtypes
DESCRIPTION:Dear all\, \nThe next IBEC Seminar will take place on Wednesday 05th October at 10:00\, when David Odde\, from Department of Biomedical Engineering at University of Minnesota\, will be talking about «Differential migration mechanics and immune response of glioblastoma subtypes». \nDavid Odde\, Department of Biomedical Engineering at University of Minnesota \nGlioblastoma remains a deadly cancer driven by invasion of tumor cells into the brain. Transcriptomic analyses have revealed distinct molecular subtypes\, but mechanistic and targetable differences that explain clinical differences are not clear. Using a state-of-the-art immunocompetent mouse model for glioblastoma – where tumors are induced by injection of plasmids containing human glioblastoma subtype-defining genetic drivers in a wild-type background – we found that\, as predicted by the motor-clutch model for cell migration (Klank et al.\, Cell Rep\, 2017)\, mesenchymal glioma cells are more spread\, generate larger traction forces\, and migrate faster in brain tissue compared to proneural cells. Despite their fast migration and comparable proliferation rate in vitro\, mice with mesenchymal tumors live longer than mice with proneural tumors\, which was correlated with an immune response in the mesenchymal mice that included T cell-mediated killing of cancer cells\, similar to human tumors. Thus\, mesenchymal tumors have aggressive migration\, but are relatively immunologically ‘hot’ which suppresses net proliferation\, features which are captured by our Brownian Dynamics tumor simulator (Klank et al.\, Conv Sci Phys Oncol\, 2018). These two features counteract each other and may explain the lack of a strong survival difference between subtypes clinically\, while also opening up new opportunities for subtype-specific therapies.
URL:https://www.pcb.ub.edu/esdeveniment/differential-migration-mechanics-and-immune-response-of-glioblastoma-subtypes/
LOCATION:Edifici Torres R+D+I\, Torre I Planta 11\, C/ Baldiri Reixac 4-8\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/ibec.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221007T120000
DTEND;TZID=Europe/Madrid:20221007T140000
DTSTAMP:20220927T083635Z
CREATED:20220927T083624Z
LAST-MODIFIED:20220927T083635Z
UID:77341-1665144000-1665151200@www.pcb.ub.edu
SUMMARY:Systemic regulation of tissue physiology by circadian rhythms during homeostasis and aging
DESCRIPTION:Speaker: Dr. Salvador Aznar Benitah – Group Leader – Stem Cells and Cancer Lab – Aging and Metabolism Programme – IRB Barcelona
URL:https://www.pcb.ub.edu/esdeveniment/systemic-regulation-of-tissue-physiology-by-circadian-rhythms-during-homeostasis-and-aging/
LOCATION:Edifici Torres R+D+I\, Auditori Antoni Caparrós\, C/ Baldiri Reixac 4-8\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/09/irb-4-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221014T100000
DTEND;TZID=Europe/Madrid:20221014T120000
DTSTAMP:20221010T124814Z
CREATED:20221010T124802Z
LAST-MODIFIED:20221010T124814Z
UID:77784-1665741600-1665748800@www.pcb.ub.edu
SUMMARY:Peptides and bioinstructive polymers on surfaces for prevention of oral infections
DESCRIPTION:Conrado Aparicio\, Faculty of Odontology\, UIC Barcelona and Associated Researcher – IBEC \nOral infections are the most prevalent infectious diseases worldwide. We have explored bioinspired modification of surfaces of restorative/regenerative materials and implants as well as dental tissues to address oral infections by harnessing the biomolecular toolbox –oligopeptides\, proteins\, recombinamers\, … and thus\, mitigating the worldwide threat of antimicrobial resistance. \nOne of our strategies aimed at exploiting secondary structure and self-assembly of anti-biofilm peptides and recombinamers to increase anti-biofilm potency vs relevant oral biofilms and to form highly hydrophobic interfaces to obtain dual-action surfaces to address infection in dental peri-tisular and peri-implant sites. \nAlternatively\, we have found inspiration in the natural junction at the tooth-oral mucosa interface. Teeth\, long-lasting percutaneous organs\, feature soft tissue attachment through adhesive structures\, hemidesmosomes\, in the junctional epithelium basement membrane adjacent to teeth. This soft tissue attachment prevents bacterial infection of the tooth despite the rich – and harsh – microbial composition of the oral cavity. Consequently\, we have tapped basement membrane peptides known to engage specific integrins as well as synthesized new bioinstructive photocurable resins that stimulate formation of hemidesmosomes on synthetic and natural surfaces. \nWe recently have also combined those strategies with immunomodulatory regulation to reduce inflammation triggered by pathogenic biofilms causing oral infections.
URL:https://www.pcb.ub.edu/esdeveniment/peptides-and-bioinstructive-polymers-on-surfaces-for-prevention-of-oral-infections/
LOCATION:Edifici Torres R+D+I\, Torre I Planta 11\, C/ Baldiri Reixac 4-8\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/ibec-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221017T110000
DTEND;TZID=Europe/Madrid:20221017T130000
DTSTAMP:20221028T064413Z
CREATED:20221028T064354Z
LAST-MODIFIED:20221028T064413Z
UID:78593-1666004400-1666011600@www.pcb.ub.edu
SUMMARY:Immunotherapies using antibody engineering: new targets\, strategies\, and challenges
DESCRIPTION:During the week\, the 14th Annual Protein & Antibody Engineering Summit (PEGS) Europe will be held in Barcelona. Thus\, that week the city will be gathering protein engineering and biotherapeutics experts in this international event.  \nThe field of antibody engineering is at an exciting time in its evolution\, with next-generation therapies being developed and entering the market\, major advances in technology\, and a wealth of discovery-stage and clinical evidence supporting the development of safe\, highly effective treatments for unmet medical needs. CataloniaBio & HealthTech contributes to bringing knowledge in an in-depth discussion roundtable with relevant speakers from our community\, moderated by Sino Biological\, on antibody engineering new targets\, strategies\, and challenges within immunotherapy.
URL:https://www.pcb.ub.edu/esdeveniment/immunotherapies-using-antibody-engineering-new-targets-strategies-and-challenges/
LOCATION:Edifici Torres R+D+I\, Auditori Antoni Caparrós\, C/ Baldiri Reixac 4-8\, Barcelona\, Barcelona\, 08028\, Espanya
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/catalo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221019T093000
DTEND;TZID=Europe/Madrid:20221019T130000
DTSTAMP:20220907T083653Z
CREATED:20220907T083609Z
LAST-MODIFIED:20220907T083653Z
UID:76661-1666171800-1666184400@www.pcb.ub.edu
SUMMARY:Encuentro B2B online digital BIO: Exploración\, análisis y prospectiva de la biodiversidad Cataluña
DESCRIPTION:El próximo 19 de octubre se celebrará el “Encuentro B2B online digital BIO: Exploración\, análisis y prospectiva de la biodiversidad Cataluña” que tendrá como protagonistas a las empresas y entidades de Cataluña que destacan por la aplicación de las tecnologías digitales disruptivas en el sector de la Biotecnología. \nEl evento se enmarca en las actividades enmarcadas en la Plataforma Tecnológica Española de Tecnologías Disruptivas (DISRUPTIVE) con la colaboración de la Asociación de Parques Científicos y Tecnológicos de España (APTE). \nEl encuentro se realizará en formato online a través de la plataforma ZOOM de 9:30 a 13:00 h con el siguiente programa: \n\n09:30-09:40    Presentación Plataforma Tecnológica de Tecnologías Disruptivas\n09:40-10:05   Presentación Programas Ayudas Agencia Estatal de Investigación\n10:05-10:35    Presentación Programa Ayudas CDTI\n10:35-11:00    Presentación Asebio (pendiente confirmación)\n11:00-11:30    Casos prácticos de aplicación empresarial de tecnologías disruptivas\n\n  \nEncuentros bilaterales: \n\n11:40-13:00    Encuentros bilaterales\n\nSi eres una entidad dedicada a la aplicación de las tecnologías digitales disruptivas en el sector de la Biotecnología y estás interesada en participar en los encuentros bilaterales\, debes inscribirte en el siguiente link. El plazo de inscripción para la participación en los encuentros bilaterales termina el 21 de septiembre de 2022. \nSi solo estás interesado en asistir a la primera parte de ponencias\, debes inscribirte en el siguiente link. \n  \n¿Quieres participar en DISRUPTIVE? Participa\, colabora y benefíciate de lo que te puede aportar esta plataforma: PARTICIPA
URL:https://www.pcb.ub.edu/esdeveniment/encuentro-b2b-online-digital-bio-exploracion-analisis-y-prospectiva-de-la-biodiversidad-cataluna/
LOCATION:Online
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/09/DISRUPTIVE_agenda.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221019T110000
DTEND;TZID=Europe/Madrid:20221019T133000
DTSTAMP:20220728T083343Z
CREATED:20220728T082846Z
LAST-MODIFIED:20220728T083343Z
UID:76323-1666177200-1666186200@www.pcb.ub.edu
SUMMARY:Strategies and approaches to optimize non-clinical development for cell and gene therapies
DESCRIPTION:Barcelona Science Park and Labcorp organize an event to discuss strategies and approaches to optimize non-clinical development for cell and gene therapies with two main keynotes and a roundtable with a panel of experts. At the end of the event a brunch will be served for attendants. \n11:00 -11:10 Welcome. Anna Serra\, PhD\, Commercialization & Communication Director\, Barcelona Science Park and Gareth Diggins\, Senior Business Development Director\, LabCorp. \n11:10 – 11:30 Strategies and Approaches to Optimize Non-clinical Development for Cell and Gene Therapies. Bruce Hamilton\, PhD\, MSc\, Drug Development – Team Leader\, Early Phase Development Solutions\, Labcorp Drug Development. \n11:30 – 11:50 Maximizing Analytical Assay Reliability for Regulatory Approval of Cell and Gene Therapy Products. Paul Byrne\, MSc – Associate Director\, Enterprise Cell & Gene Therapy. \n11:50 – 12:20 Roundtable Q&A (Speakers TBD). \n12:20 – 13:30 Brunch & networking.
URL:https://www.pcb.ub.edu/esdeveniment/strategies-and-approaches-to-optimize-non-clinical-development-for-cell-and-gene-therapies/
LOCATION:Edifici Cluster II\, Sala Dolors Aleu\, Avinguda Dr. Marañón 6-8\, Barcelona\, Barcelona\, 08028
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/07/pcb-labcorp-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221020T090000
DTEND;TZID=Europe/Madrid:20221020T113000
DTSTAMP:20221006T095755Z
CREATED:20221006T094832Z
LAST-MODIFIED:20221006T095755Z
UID:77676-1666256400-1666265400@www.pcb.ub.edu
SUMMARY:BAKE SALE per recaptar fons per a l'Asociación Española contra la Meningitis (AEM)
DESCRIPTION:L’Associació Espanyola contra la Meningitis (AEM) és una associació sense ànim de lucre creada l’any 2016 per lluitar contra la meningitis a Espanya i a la resta del món mitjançant la promoció i finançament de diferents campanyes\, formació especialitzada\, recerca de causes\, prevenció\, detecció i tractament contra la meningitis i suport a les persones afectades. La Bake Sale d’enguany aprofita que el 5 d’octubre és el Dia Mundial contra la Meningitis i és fruit de la col·laboració entre els PCBakers i New Born Solutions. Tindrà lloc dijous 20 d’octubre a l’entrada del Clúster II (costat av. Doctor Marañón) de 9.00 a 11.30 h. Com sempre us animem a portar la vostra tassa\, plat o tàper. Les donacions podran fer-se en efectiu i per Bizum\, i tots els diners recaptats aniran a l’AEM.
URL:https://www.pcb.ub.edu/esdeveniment/bake-sale-per-recaptar-fons-per-a-lasociacion-espanola-contra-la-meningitis-aem/
LOCATION:Parc Científic de Barcelona\, Recepció Cluster II\, Av. Dr. Marañón 8\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/bAkeeee-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221020T170000
DTEND;TZID=Europe/Madrid:20221020T200000
DTSTAMP:20221013T125059Z
CREATED:20221013T125047Z
LAST-MODIFIED:20221013T125059Z
UID:77969-1666285200-1666296000@www.pcb.ub.edu
SUMMARY:Acto 15 Aniversario de Fundación GAEM
DESCRIPTION:El acto estará presidido por el honorable Sr. Josep M. Argimon i Pallàs\, Conseller de Salut de la Generalitat de Catalunya y contará con la asistencia del Dr. Cristóbal Belda\, Director del Instituto de Investigación Carlos III\, entre otras autoridades y personalidades de la salud y la ciencia. Conferenciante invitado: Dr. Pablo Villoslada\, IDIBAPS – Hospital Clínic Barcelona y Universidad de Stanford. \n  \n*El auditorio está habilitado para personas con movilidad reducida. Por favor\, indíquelo en la inscripción.
URL:https://www.pcb.ub.edu/esdeveniment/acto-15-aniversario-de-fundacion-gaem/
LOCATION:Edifici Torres R+D+I\, Auditori Antoni Caparrós\, C/ Baldiri Reixac 4-8\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/gaem.jpg
ORGANIZER;CN="Fundaci%C3%B3n GAEM":MAILTO:info@fundaciongaem.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221024T120000
DTEND;TZID=Europe/Madrid:20221024T140000
DTSTAMP:20221021T075321Z
CREATED:20221021T075321Z
LAST-MODIFIED:20221021T075321Z
UID:78270-1666612800-1666620000@www.pcb.ub.edu
SUMMARY:Enhancement of anti-tumor immunity in RAS-addicted cancers with tri-complex RAS(ON) inhibitors
DESCRIPTION:Speaker: Elsa Quintana\, Pharm.D.\, Ph.D. Senior Director Cancer Immunology\, Revolution Medicines\, Redwood City\, USA \nRAS mutations (RASMUT)\, the most frequent oncogenic alterations in human cancers\, promote carcinogenesis through sustained cellular proliferation and also shape the tumor microenvironment to allow cancer cells to evade an anti-tumor immune response. \nRAS oncoproteins may be targeted with mutant selective\, tri-complex RAS(ON) inhibitors or tri-complex RASMULTI(ON) inhibitors. These inhibitors have distinct preclinical profiles and potential clinical applications. KRASG12C(ON) mutant-selective inhibitors potently inhibit the RAS pathway in KRASG12C mutant cancer cells and indirectly modulate the TME by impacting the secretion of cytokines and the expression of cancer cell surface proteins. A RASMULTI(ON) inhibitor targets not only multiple RAS mutants but also wild-type RAS\, a critical signaling node both in tumors and normal immune cells. We have evaluated the effects of KRASG12C(ON) and RASMULTI(ON) inhibitors on the TME and anti-tumor immunity in murine tumor models in vivo. \nOral daily administration of either a KRASG12C(ON) inhibitor or a RASMULTI(ON) inhibitor drove complete tumor regressions and synergized with anti-PD-1 in vivo in an immune-sensitive colorectal KRASG12C mutant model. Re-challenge experiments demonstrated that both inhibitor classes induce immunological memory. RAS inhibition with mutant-selective or RASMULTI(ON) inhibitors decreased the expression of checkpoint molecules\, stem cell markers and proliferation markers on KRASG12C mutant tumor cells in vitro and in vivo. Single-agent therapy induced an increase of CD8+ T-cells and dendritic cells (DCs) and a decrease in pro-tumorigenic M2 macrophages and myeloid derived suppressor cells (MDSCs) in the tumor. In tumors treated with KRASG12C(ON) inhibitors this effect on immune cell infiltration was\, in part\, mediated through the modulation of tumor secreted cytokines. A RASMULTI(ON) inhibitor induced a more pronounced decrease in M2 macrophages which raised the question whether\, in addition to the impact on cytokine production\, there was also a direct effect of RAS inhibition on macrophages. A RASMULTI(ON) inhibitor\, similar to SHP2 inhibitors (Quintana\, E. et al\, 2020)\, but unlike a mutant selective RAS(ON) inhibitor\, directly and selectively reduced the viability of M2\, but not M1 macrophages in vitro. To interrogate if these properties can be leveraged to convert the TME of an immune-suppressive tumor we characterized the impact of RAS(ON) inhibitors in an anti-PD-1-refractory lung KRASG12C mutant model; we observed a significant conversion of the TME in favor of anti-tumor immunity in this model. \nThese preclinical data suggest that mutant-selective and\, more profoundly\, RASMULTI(ON) inhibitors promote the conversion of an immune-suppressive into an ‘immune-hot’ TME in RAS-mutant tumors.
URL:https://www.pcb.ub.edu/esdeveniment/enhancement-of-anti-tumor-immunity-in-ras-addicted-cancers-with-tri-complex-rason-inhibitors/
LOCATION:Edifici Cluster I\, Aula Fèlix Serratosa\, C/ Baldiri Reixac 10-12\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/irb-3.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221025T090000
DTEND;TZID=Europe/Madrid:20221025T140000
DTSTAMP:20221024T101510Z
CREATED:20221024T101408Z
LAST-MODIFIED:20221024T101510Z
UID:78370-1666688400-1666706400@www.pcb.ub.edu
SUMMARY:Mental Health Innovation Day de la Xarxa TECSAM
DESCRIPTION:La Xarxa TECSAM organitza el I Mental Health Innovation Day el dimarts dia 25 d’octubre. Es tracta d’una jornada presencial i oberta a tot l’ecosistema d’innovació en salut mental que donarà espai als diferents grups de recerca de la Xarxa\, tant de l’àmbit clínic com tecnològic\, per presentar els projectes més destacats desenvolupats enguany. Serà un punt de trobada i contacte entre tots els stakeholders del sector de la salut mental i la innovació.
URL:https://www.pcb.ub.edu/esdeveniment/mental-health-innovation-day-de-la-xarxa-tecsam/
LOCATION:Edifici Cluster II\, Sala Dolors Aleu\, Avinguda Dr. Marañón 6-8\, Barcelona\, Barcelona\, 08028
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/xarxa.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221026T093000
DTEND;TZID=Europe/Madrid:20221026T113000
DTSTAMP:20220822T115902Z
CREATED:20220822T115847Z
LAST-MODIFIED:20220822T115902Z
UID:76539-1666776600-1666783800@www.pcb.ub.edu
SUMMARY:BioExpert Network\, la puerta al mundo del emprendimiento y la inversión
DESCRIPTION:BioExpert Network\, la puerta al mundo del emprendimiento y la inversión científica \n¿Eres científico y te interesa el mundo del emprendimiento? ¿Te gustaría conocer de cerca y participar en el ecosistema de inversión en el sector de la salud? ¿Quieres posicionarte en el ámbito del emprendimiento científico? El Parc Científic de Barcelona y Capital Cell organizan una sesión informativa para presentar una oportunidad única para científicos inquietos: la BioExpert Network. En la sesión\, dirigida a profesionales con formación científica en ciencias de la vida\, se presentará la BioExpert Network\, como participar y los beneficios que aporta. \nLa BioExpert Network es una red internacional de evaluación de startups científicas que cuenta con más de 2.600 expertos en salud (científicos\, emprendedores\, inversores especializados\, abogados\, etc.). Es una pieza clave del proceso de selección de las propuestas de inversión que posteriormente serán publicadas en Capital Cell. \nAdemás de contribuir al desarrollo científico\, formar parte de la BioExpert Network va acompañado de beneficios como participaciones gratis en las empresas\, acceso a información anticipada sobre nuevas oportunidades de inversión y a una amplia red de contactos. \nAgenda \n09:30-09:35 Bienvenida. Anna Serra\, directora de Comercialización y Comunicación del Parc Científic de Barcelona. \n09:35-09:45 Inversión en salud y biotech – ¿Qué es Capital Cell?. Daniel Oliver\, director de Capital Cell. \n09:45-10:15 BioExpert Network – el elemento clave en la evaluación de startups. Daniel Oliver\, director de Capital Cell. \n10:15-10:45 Qué significa ser un BioExpert. Bioexperto TBC. \n10:45-11:00 Turno de preguntas \n11:00-11:30 Café-networking
URL:https://www.pcb.ub.edu/esdeveniment/bioexpert-network-la-puerta-al-mundo-del-emprendimiento-y-la-inversion/
LOCATION:Edifici Cluster II\, Sala Dolors Aleu\, Avinguda Dr. Marañón 6-8\, Barcelona\, Barcelona\, 08028
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/08/call.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221026T103000
DTEND;TZID=Europe/Madrid:20221026T133000
DTSTAMP:20221007T115006Z
CREATED:20221007T114936Z
LAST-MODIFIED:20221007T115006Z
UID:77751-1666780200-1666791000@www.pcb.ub.edu
SUMMARY:Curso de seguridad en la utilización de gases a presión y líquidos criogénicos
DESCRIPTION:El mal uso de gases como el Helio\, Óxido Nitroso o Nitrógeno Líquido para su consumo confines lúdicos en lugares de ocio\, puede provocar asfixia\, quemaduras o narcosis\, entre otros efectos.
URL:https://www.pcb.ub.edu/esdeveniment/curso-de-seguridad-en-la-utilizacion-de-gases-a-presion-y-liquidos-criogenicos/
LOCATION:Edifici Cluster I\, Aula Fèlix Serratosa\, C/ Baldiri Reixac 10-12\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/curso.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221027T130000
DTEND;TZID=Europe/Madrid:20221027T170000
DTSTAMP:20221021T080654Z
CREATED:20221021T080645Z
LAST-MODIFIED:20221021T080654Z
UID:78281-1666875600-1666890000@www.pcb.ub.edu
SUMMARY:Servei de fisioteràpia per a la Comunitat del PCB
DESCRIPTION:Cost de l’activitat: Els imports són de 18€ per una sessió de 30 minuts i 35€ per una sessió de 55 minuts. El PCB cedeix gratuïtament una sala perquè un fisioterapeuta diplomat pugui fer les visites. L’import de l’activitat es íntegrament per al professional. \n  \nCalendari\, horaris de l’activitat i registre aquí.
URL:https://www.pcb.ub.edu/esdeveniment/servei-de-fisioterapia-per-a-la-comunitat-del-pcb/
LOCATION:Parc Científic de Barcelona\, Recepció Cluster II\, Av. Dr. Marañón 8\, Barcelona\, Barcelona\, 08028\, Espanya
CATEGORIES:Esdeveniment PCB
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/Fisio.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221027T170000
DTEND;TZID=Europe/Madrid:20221027T190000
DTSTAMP:20221021T075546Z
CREATED:20220616T133134Z
LAST-MODIFIED:20221021T075546Z
UID:75255-1666890000-1666897200@www.pcb.ub.edu
SUMMARY:Regulation of hematopoietic stem cell dormancy
DESCRIPTION:Speaker: Nina Cabezas-Wallscheid\, Ph.D. Group Leader\, Regulation of Hematopoietic Stem Cell Dormancy\, Max Planck Institute\, Freiburg\, Germany. \nBone marrow hematopoietic stem cells (HSCs) are vital for the maintenance of hematopoiesis. In inbred mice housed in gnotobiotic facilities\, the top of the hematopoietic hierarchy is occupied by dormant HSCs\, which reversibly exit quiescence during stress. Still\, whether HSC dormancy exists in human remains unclear. Our recent work shows the existence and relevance of dormancy in human HSCs and identifies the hyaluronic acid-GPRC5C signalling axis as an essential component controlling the HSC state (Zhang et al.\, Nature Cell Biology 2022). Further\, HSCs rely on complex regulatory networks to preserve their function. Due to the scarcity of HSCs\, technical challenges have limited our insights into the interplay between HSC metabolism and their transcriptional and epigenetic regulation. We recently established and integrated low-input multi-layer OMICs data revealing distinct metabolic and epigenetic hubs that are enriched in HSCs and their downstream multipotent progenitors (Schönberger et al.\, Cell Stem Cell 2022). Mechanistically\, we uncover a non-classical retinoic acid signaling axis that regulates HSC identity. Our findings emphasize how a single metabolite controls stem cell fate by instructing epigenetic and transcriptional attributes.
URL:https://www.pcb.ub.edu/esdeveniment/regulation-of-hematopoietic-stem-cell-dormancy/
LOCATION:Edifici Cluster I\, Aula Fèlix Serratosa\, C/ Baldiri Reixac 10-12\, Barcelona\, Barcelona\, 08028\, Espanya
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/06/openbuena.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20221028T120000
DTEND;TZID=Europe/Madrid:20221028T140000
DTSTAMP:20221024T105024Z
CREATED:20221024T105013Z
LAST-MODIFIED:20221024T105024Z
UID:78387-1666958400-1666965600@www.pcb.ub.edu
SUMMARY:The roles of mobile DNA in human cancer
DESCRIPTION:Speaker: Jose Tubio\, Ph.D. Group Leader\, Mobile Genomes lab\, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS)\, University of Santiago de Compostela\, Spain. \nSomatic retrotransposition represents the most frequent class of structural variation in some human cancers. For the last 10 years\, we have illuminated two relevant mutational mechanisms by which somatic RT can provide the mutations that a cancer clone requires to survive and grow (PMID: 25082706; PMID: 32024998). Currently\, our research focuses on the use of long-read sequencing and chromatin conformation capture techniques for the discovery of novel\, previously unreported mutational roles of somatic retrotransposition in human cancer. \nJose Tubio has carried out his research at the forefront of cancer genomics\, being involved in the discovery of new cancer genes in hematological cancers and bone cancers\, the identification of new mechanisms of mutation\, the characterization of mechanisms that drive the dynamics of metastasis\, the identification of genes that drive transmissible cancers\, and the identification of early genetic mutations that occur in normal tissues and their role in tumour transformation.
URL:https://www.pcb.ub.edu/esdeveniment/the-roles-of-mobile-dna-in-human-cancer/
LOCATION:Edifici Cluster I\, Aula Fèlix Serratosa\, C/ Baldiri Reixac 10-12\, Barcelona\, Barcelona\, 08028\, Espanya
ATTACH;FMTTYPE=image/jpeg:https://www.pcb.ub.edu/wp-content/uploads/2022/10/irb.jpg
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END:VCALENDAR