{"id":39247,"date":"2019-03-04T00:00:00","date_gmt":"2019-03-03T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/\/una-nueva-tecnica-permite-focalizar-la-accion-de-farmacos-mediante-luz-infrarroja\/"},"modified":"2020-11-16T16:23:12","modified_gmt":"2020-11-16T15:23:12","slug":"una-nueva-tecnica-permite-focalizar-la-accion-de-farmacos-mediante-luz-infrarroja","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/es\/una-nueva-tecnica-permite-focalizar-la-accion-de-farmacos-mediante-luz-infrarroja\/","title":{"rendered":"Una nueva t\u00e9cnica permite focalizar la acci\u00f3n de f\u00e1rmacos mediante luz infrarroja"},"content":{"rendered":"

Tener el control absoluto de la actividad de una mol\u00e9cula en un organismo. Decidir cu\u00e1ndo, d\u00f3nde y c\u00f3mo se activa un f\u00e1rmaco. Estas son algunas de las metas que se espera alcanzar con las llamadas mol\u00e9culas fotoconmutables, unos compuestos que, en presencia de determinadas ondas de luz, cambian sus propiedades. Hoy, gracias a los resultados de una investigaci\u00f3n liderada por el IBEC\u00a0junto a la UAB, la comunidad cient\u00edfica est\u00e1 m\u00e1s cerca de lograrlo.<\/p>\n

Por primera vez los cient\u00edficos han podido activar, con una eficiencia de casi el 100% y utilizando l\u00e1seres de luz infrarroja, mol\u00e9culas fotoconmutables localizadas en el interior del tejido neuronal. \u201cSe trata de un desarrollo que abre la puerta a un gran n\u00famero de aplicaciones. Desde f\u00e1rmacos que \u00fanicamente act\u00faan en el punto de nuestro cuerpo que es iluminado y, por tanto, libres de efectos secundarios no deseados en otras regiones; hasta el control espacial y temporal de cualquier prote\u00edna cuyo funcionamiento queramos estudiar en el contexto de un organismo\u201d, comenta Pau Gorostiza, profesor de investigaci\u00f3n ICREA y responsable del Grupo de Nanosondas y Nanoconmutadores del IBEC.\u00a0<\/p>\n

\u25ba Art\u00edculo de referencia:<\/strong>\u00a0Gisela Cabr\u00e9, Aida Garrido-Charles, Miquel Moreno, Miquel Bosch, Montserrat Porta-de-la-Riva, Michael Krieg, Marta Gasc\u00f3n-Moya, N\u00faria Camarero, Ricard Gelabert, Jos\u00e9 M. Lluch, F\u00e9lix Busqu\u00e9, Jordi Hernando, Pau Gorostiza & Ramon Alib\u00e9s. \u00abRationally designed azobenzene photoswitches for efficient two-photon neuronal excitation<\/a>\u00ab. Nature Communications volume 10, Article number: 907 (2019).<\/p>\n

\u25ba M\u00e1s informaci\u00f3n: <\/strong>Web del IBEC [+]<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Un equipo cient\u00edfico liderado por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC<\/a>) y la Universitat Aut\u00f2noma de Barcelona (UAB<\/a>) logra activar con gran eficiencia mol\u00e9culas localizadas en el interior de tejidos celulares mediante la estimulaci\u00f3n de dos fotones con l\u00e1seres de luz infrarroja. La investigaci\u00f3n se ha publicado en\u00a0Nature Communications.<\/p>\n

\u00a0<\/p>\n","protected":false},"author":1,"featured_media":27444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-39247","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sin-categorizar"],"acf":[],"yoast_head":"\nUna nueva t\u00e9cnica permite focalizar la acci\u00f3n de f\u00e1rmacos mediante luz infrarroja - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/es\/una-nueva-tecnica-permite-focalizar-la-accion-de-farmacos-mediante-luz-infrarroja\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Una nueva t\u00e9cnica permite focalizar la acci\u00f3n de f\u00e1rmacos mediante luz infrarroja - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"Un equipo cient\u00edfico liderado por el Instituto de Bioingenier\u00eda de Catalu\u00f1a (IBEC) y la Universitat Aut\u00f2noma de Barcelona (UAB) logra activar con gran eficiencia mol\u00e9culas localizadas en el interior de tejidos celulares mediante la estimulaci\u00f3n de dos fotones con l\u00e1seres de luz infrarroja. 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