{"id":39190,"date":"2020-04-20T00:00:00","date_gmt":"2020-04-19T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/\/som-biotech-valida-tres-candidatos-a-farmacos-para-el-covid-19-con-la-ewha-womans-university\/"},"modified":"2020-11-16T16:22:58","modified_gmt":"2020-11-16T15:22:58","slug":"som-biotech-valida-tres-candidatos-a-farmacos-para-el-covid-19-con-la-ewha-womans-university","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/es\/som-biotech-valida-tres-candidatos-a-farmacos-para-el-covid-19-con-la-ewha-womans-university\/","title":{"rendered":"SOM Biotech valida tres candidatos a f\u00e1rmacos para el COVID-19 con la Ewha Womans University"},"content":{"rendered":"<p>La compa\u00f1\u00eda biofarmac\u00e9utica SOM Biotech \u2013con sede en el Parc Cient\u00edfic de Barcelona (PCB) y especializada en el desarrollo y descubrimiento de f\u00e1rmacos\u2013 anuncia la validaci\u00f3n in vitro de tres candidatos como nuevas terapias para el tratamiento del COVID-19. Los tres compuestos son f\u00e1rmacos en fase cl\u00ednica que inhiben la proteasa principal del SARS-CoV-2 y sus estudios en pacientes pueden iniciarse de inmediato.\u00a0<\/p>\n<p>SOM Biotech ha identificado los inhibidores de las proteasas 3CL de los virus SARS-CoV-2, SARS-CoV y MERS-CoV como potenciales candidatos para tratar el COVID-19, utilizando su tecnolog\u00eda <a href=\"https:\/\/sombiotech.com\/our-approach-artificial-intelligence-based-technology\/\" target=\"_blank\" rel=\"noopener noreferrer\">SOMAIPRO<\/a> basada en inteligencia artificial. El descubrimiento de la actividad de los f\u00e1rmacos es el resultado de los trabajos de investigaci\u00f3n desarrollados en colaboraci\u00f3n con el Departamento de Ciencias Farmac\u00e9uticas de la Facultad de Farmacia de la Ewha Womans University de Corea del Sur, dirigido por el profesor Dong-Hae Shin. E<\/p>\n<p>Entre los tres f\u00e1rmacos identificados y validados, uno \u2013Eravacycline TP-434 \u2013es un antibi\u00f3tico a base de tetraciclina, ya aprobado. El segundo \u2013Prexasertib LY-2606368\u2013 se encuentra en desarrollo cl\u00ednico para indicaciones oncol\u00f3gicas, y el tercero es un compuesto natural en investigaci\u00f3n para el tratamiento de la hiperlipidemia.\u00a0<\/p>\n<p>Los tres f\u00e1rmacos pueden ser reposicionados para tratar el COVID-19 y la compa\u00f1\u00eda est\u00e1 trabajando para iniciar los ensayos en pacientes lo antes posible. Ya se ha presentado la solicitud de patente de m\u00e9todo de uso para los tres f\u00e1rmacos a nivel mundial.\u00a0<\/p>\n<p>Seg\u00fan Ra\u00fal Insa, CEO y fundador de SOM Biotech: \u201cHemos aunado esfuerzos con el profesor Dong-Hae Shin de la Ewha Womans University para aprovechar nuestro conocimiento m\u00e9dico y cient\u00edfico con el objetivo de encontrar nuevas soluciones para el COVID-19. Con nuestra tecnolog\u00eda de identificaci\u00f3n de mol\u00e9culas basada en inteligencia artificial hemos validado compuestos activos para tratar el coronavirus. Trabajamos en el r\u00e1pido desarrollo de estos medicamentos para poder proporcionar a los pacientes tratamientos efectivos y seguros contra el COVID-19 lo antes posible\u201d.\u00a0<\/p>\n<p>Por su parte el profesor Dong-Hae Shin de la Ewha Womans University declara: \u201cEstamos muy orgullosos de trabajar en tratamientos prometedores contra el COVID-19 y de contribuir a encontrar soluciones efectivas, seguras y r\u00e1pidas, dada la importancia de la situaci\u00f3n actual de la pandemia. Decidimos trabajar con SOM Biotech ya que estamos comprometidos a abordar esta pandemia del COVID-19 con el apoyo de socios con tecnolog\u00edas innovadoras y excelentes conocimientos.\u201d\u00a0<\/p>\n<p><span style=\"font-size: 16px\"><strong>Reposicionamiento de f\u00e1rmacos con inteligencia artificial\u00a0<\/strong><\/span><\/p>\n<p>SOM Biotech es una biofarmac\u00e9utica de referencia mundial en reposicionamiento de f\u00e1rmacos \u2013identificaci\u00f3n de nuevas actividades terap\u00e9uticas de medicamentos aprobados para otra indicaci\u00f3n \u2013a trav\u00e9s de su plataforma propia de inteligencia artificial\u2013 lo que reduce considerablemente los costes de inversi\u00f3n y tiempo de llegada de nuevos tratamientos al mercado.\u00a0<\/p>\n<p>Desde su creaci\u00f3n en 2009, ha captado m\u00e1s de 12 M\u20ac procedentes de capital p\u00fablico y privado. En la \u00faltima ronda de financiaci\u00f3n, que cerr\u00f3 en marzo de 2019, levant\u00f3 7 M\u20ac.\u00a0<\/p>\n<p>La compa\u00f1\u00eda ha desarrollado m\u00e1s de 40 proyectos y ha firmado acuerdos de licencia mundial de dos de sus productos: el SOM0226, para el tratamiento de la Amiloidosis por Transtiretina (ATTR), y el SOM0777, para determinados c\u00e1nceres cerebrales.<\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p><a href=\"http:\/\/www.pcb.ub.edu\/portal\/es\/empresa?p_p_id=detallempresa_WAR_empleatsempresesportlet&amp;p_p_state=MAXIMIZED&amp;_detallempresa_WAR_empleatsempresesportlet_empresaId=ENT_007884&amp;_detallempresa_WAR_empleatsempresesportlet_redirect=%2Fportal%2Fca%2Fentitats\" target=\"_blank\" rel=\"noopener noreferrer\">SOM Biotech<\/a>, con sede en\u00a0el Parc Cient\u00edfic de Barcelona, ha identificado y validado <em>in vitro<\/em> \u2013en collaboraci\u00f3n\u00a0con la <a href=\"https:\/\/www.ewha.ac.kr\/ewhaen\/index.do\" target=\"_blank\" rel=\"noopener noreferrer\">Ewha Womans University<\/a> de Corea del Sur\u2013 tres f\u00e1rmacos que pueden ser\u00a0reposicionats\u00a0para tratar el\u00a0SARS-CoV-2, utilizando su tecnolog\u00eda de inteligencia artificial.\u00a0La\u00a0biofarmac\u00e9utica\u00a0\u2013una de las compa\u00f1\u00edas de referencia internacional en reposicionamento de f\u00e1rmacos\u2013 ha presentado la solicitud de patente de m\u00e9todo de uso para los tres compuestos a nivel mundial y trabaja para iniciar los ensayos en pacientes.<\/p>\n<p>\u00a0<\/p>\n","protected":false},"author":1,"featured_media":27216,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-39190","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sin-categorizar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - 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