{"id":38833,"date":"2014-11-10T00:00:00","date_gmt":"2014-11-09T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/\/inveready-entra-en-el-capital-de-la-biotecnologica-avizorex\/"},"modified":"2014-11-10T00:00:00","modified_gmt":"2014-11-09T23:00:00","slug":"inveready-entra-en-el-capital-de-la-biotecnologica-avizorex","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/es\/inveready-entra-en-el-capital-de-la-biotecnologica-avizorex\/","title":{"rendered":"Inveready entra en el capital de la biotecnol\u00f3gica Avizorex"},"content":{"rendered":"

Avizorex, que fue una de las participantes de la pasada edici\u00f3n del programa BioEmprenedorXXI \u2013iniciativa impulsada por Barcelona Activa, Biocat y Fundaci\u00f3n \u00abla Caixa\u00bb\u2013 se dedica al desarrollo farmac\u00e9utico en el \u00e1mbito de la oftalmolog\u00eda. Su investigaci\u00f3n se centra en la creciente problem\u00e1tica de la sequedad ocular con una aproximaci\u00f3n terap\u00e9utica innovadora que ha sido validada en modelos animales y que se basa en la activaci\u00f3n de los termoreceptors del fr\u00edo presentes en el ojo para estimular la lacrimaci\u00f3n basal.<\/p>\n

El descubrimiento de la\u00a0spin-off<\/em> fue publicado en la revista Nature Medicine en 2010 (doi:10.1038\/nm.2264<\/a>) y demostr\u00f3 que la estimulaci\u00f3n de una prote\u00edna llamada TRMP8 activa los receptores del fr\u00edo presentes en la superficie del ojo, aumenta la secreci\u00f3n lacrimal de forma natural y, por lo tanto, reduce la sequedad ocular.<\/p>\n

Actualmente s\u00f3lo existe un f\u00e1rmaco de prescripci\u00f3n m\u00e9dica para combatir este problema. Se trata de Restasis\u00ae, de Allergan, una formulaci\u00f3n del immunosupressor gen\u00e9rico ciclosporina descubierto por la Universidad de Georgia hace 20 a\u00f1os.Tambi\u00e9n existen otros desarrollos en fases cl\u00ednicas avanzadas pero con un bajo nivel de innovaci\u00f3n. Entre los m\u00e1s prometedores encontramos MIM-D3, un antagonista de TrkA descubierto en la Universidad de McGill desarrollado por Mimetogen.<\/p>\n","protected":false},"excerpt":{"rendered":"

La firma de capital riesgo\u00a0Inveready<\/a>\u00a0ha injectado 800.000 de euros a la\u00a0spin-off<\/i>\u00a0Avizorex Pharma<\/a>, ubicada en el Parc Cient\u00edfic de Barcelona y fundada en 2013 per Patrick Tresserras y el profesor Carlos Belmonte, del\u00a0Instituto de Neurociencies de Alicante<\/a>. La inversi\u00f3n del fondo Inveready se complementar\u00e1 con ayudas p\u00fablicas que elevan el importe total de la ronda de financiaci\u00f3n a 2,5 milions de euros.<\/p>\n

\u00a0<\/p>\n

\u00a0<\/p>\n","protected":false},"author":1,"featured_media":25817,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-38833","post","type-post","status-publish","format-standard","has-post-thumbnail"],"acf":[],"yoast_head":"\nInveready entra en el capital de la biotecnol\u00f3gica Avizorex - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/es\/inveready-entra-en-el-capital-de-la-biotecnologica-avizorex\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inveready entra en el capital de la biotecnol\u00f3gica Avizorex - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"La firma de capital riesgo\u00a0Inveready\u00a0ha injectado 800.000 de euros a la\u00a0spin-off\u00a0Avizorex Pharma, ubicada en el Parc Cient\u00edfic de Barcelona y fundada en 2013 per Patrick Tresserras y el profesor Carlos Belmonte, del\u00a0Instituto de Neurociencies de Alicante. 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