{"id":38586,"date":"2017-02-19T00:00:00","date_gmt":"2017-02-18T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/\/colaboracion-de-merus-e-irb-barcelona-para-desarrollar-anticuerpos-dirigidos-al-microambiente-tumoral\/"},"modified":"2020-11-16T16:20:41","modified_gmt":"2020-11-16T15:20:41","slug":"colaboracion-de-merus-e-irb-barcelona-para-desarrollar-anticuerpos-dirigidos-al-microambiente-tumoral","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/es\/colaboracion-de-merus-e-irb-barcelona-para-desarrollar-anticuerpos-dirigidos-al-microambiente-tumoral\/","title":{"rendered":"Colaboraci\u00f3n de Merus e IRB Barcelona para desarrollar anticuerpos dirigidos al microambiente tumoral"},"content":{"rendered":"<p>Esta colaboraci\u00f3n permite combinar la plataforma de tecnolog\u00eda\u00a0Merus Biclonics\u00a0-para el descubrimiento y desarrollo de anticuerpos biespec\u00edficos terap\u00e9uticos- con los modelos celulares y animales \u00fanicos desarrollados en el\u00a0<a href=\"http:\/\/www.irbbarcelona.org\/es\/research\/colorectal-cancer-laboratory\" target=\"_blank\" rel=\"noopener noreferrer\">Laboratorio de C\u00e1ncer Colorrectal\u00a0<\/a>del Dr. Batlle. Dicha combinaci\u00f3n facilitar\u00e1 la evaluaci\u00f3n como dianas terap\u00e9uticas de las c\u00e9lulas del estroma, en las que se apoya el crecimiento tumoral y la met\u00e1stasis.<\/p>\n<p>Esta nueva relaci\u00f3n entre IRB Barcelona y Merus se basa en un trabajo anterior establecido en el proyecto\u00a0<a href=\"https:\/\/www.irbbarcelona.org\/es\/news\/suppresstem-cinco-institutos-y-farmaceuticas-aliados-contra-el-cancer\" target=\"_blank\" rel=\"noopener noreferrer\">suppresSTEM<\/a>, un consorcio europeo para validar nuevos tratamientos contra el c\u00e1ncer colorrectal que se llev\u00f3 a cabo entre 2013 y 2016. \u00abNuestra colaboraci\u00f3n result\u00f3 en MCLA-158, un\u00a0Biclonics\u00a0dirigido a EGFR y Lgr5 que actualmente est\u00e1 en estudios de habilitaci\u00f3n-IND\u00bb, ha dicho\u00a0Mark Throsby, director cient\u00edfico de\u00a0Merus. \u00abPredecimos que el acceso a ideas y herramientas del IRB para investigar el ambiente del tumor nos ser\u00e1 extremadamente \u00fatil para descubrir y validar\u00a0Biclonics\u00a0que bloqueen la iniciaci\u00f3n y progresi\u00f3n del c\u00e1ncer metast\u00e1sico\u00bb.<\/p>\n<p>\u00abLa tecnolog\u00eda\u00a0Biclonics\u00a0de\u00a0Merus\u00a0es una plataforma prometedora para desarrollar anticuerpos biespec\u00edficos dirigidos espec\u00edficamente al estroma tumoral\u00bb, explicael investigador ICREA,\u00a0Eduard Batlle. \u00abPensamos que esta asociaci\u00f3n optimizar\u00e1 la generaci\u00f3n de terapias diferenciadas para tratar a pacientes con subtipos de tumores dif\u00edciles de tratar\u00bb.<\/p>\n<p>Esta colaboraci\u00f3n se enmarca en el\u00a0<a href=\"http:\/\/www.fundacionbotin.org\/ciencia\/ciencia.html\" target=\"_blank\" rel=\"noopener noreferrer\">Programa de Investigaci\u00f3n de la Fundaci\u00f3n Bot\u00edn,<\/a>\u00a0al que pertenece\u00a0Eduard Batlle.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El laboratorio de\u00a0Eduard Batlle\u00a0del\u00a0<a href=\"http:\/\/www.pcb.ub.edu\/portal\/es\/cerca?p_p_id=cercador_WAR_empleatsempresesportlet&amp;p_p_lifecycle=0&amp;p_p_state=maximized&amp;p_p_mode=view&amp;p_p_col_id=column-1&amp;p_p_col_count=1&amp;_cercador_WAR_empleatsempresesportlet_jspPage=%2Fhtml%2Fcommon%2Fdetall-empresa.jsp&amp;_cercador_WAR_empleatsempresesportlet_empresaId=ENT_000001&amp;_cercador_WAR_empleatsempresesportlet_redirect=%2Fportal%2Fca%2Fcerca%3Fp_p_id%3Dcercador_WAR_empleatsempresesportlet%26p_p_lifecycle%3D0%26p_p_mode%3Dview%26_cercador_WAR_empleatsempresesportlet_keywords%3Dirb%26_cercador_WAR_empleatsempresesportlet_tab%3D1\" target=\"_blank\" rel=\"noopener noreferrer\">IRB Barcelona<\/a>, con sede\u00a0en el\u00a0PCB,\u00a0y la biotecnol\u00f3gica\u00a0holandesa\u00a0<a href=\"http:\/\/www.merus.nl\/\" target=\"_blank\" rel=\"noopener noreferrer\">Merus N.V<\/a>\u00a0han anunciado\u00a0una colaboraci\u00f3n de investigaci\u00f3n para desarrollar conjuntamente nuevos agentes dirigidos al microambiente tumoral.\u00a0La asociaci\u00f3n permite combinar la plataforma tecnol\u00f3gica\u00a0<a href=\"http:\/\/www.merus.nl\/technology\/\" target=\"_blank\" rel=\"noopener noreferrer\">Merus Biclonics<\/a>\u00a0y los modelos celulares y animales desarrollados en el Laboratorio de C\u00e1ncer Colorrectal\u00a0de\u00a0Eduard Batlle\u00a0para investigar el estroma.<\/p>\n<p>\u00a0<\/p>\n","protected":false},"author":1,"featured_media":24852,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-38586","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sin-categorizar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - 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