{"id":38555,"date":"2017-07-20T00:00:00","date_gmt":"2017-07-19T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\/"},"modified":"2020-11-16T16:20:33","modified_gmt":"2020-11-16T15:20:33","slug":"hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/es\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\/","title":{"rendered":"Hacia una comprensi\u00f3n m\u00e1s profunda de la regulaci\u00f3n del genoma"},"content":{"rendered":"<p>La regulaci\u00f3n de la traducci\u00f3n\u2014el proceso mediante el cual se controla la cantidad de prote\u00edna sintetizada a partir de su ARN mensajero (ARNm)\u2014 es un paso crucial para establecer el grado de expresi\u00f3n g\u00e9nica durante eventos tales como proliferaci\u00f3n celular, diferenciaci\u00f3n, desarrollo, funciones del sistema nervioso y, tambi\u00e9n, en enfermedades como el c\u00e1ncer.<\/p>\n<p>En comparaci\u00f3n con la regulaci\u00f3n transcripcional (de ADN a ARN), el control de la traducci\u00f3n de los ARNm existentes\u2014mol\u00e9culas que contienen la informaci\u00f3n gen\u00e9tica para la s\u00edntesis de prote\u00ednas\u2014 permite una respuesta m\u00e1s r\u00e1pida a los est\u00edmulos.<\/p>\n<p>El estudio realizado\u00a0por los investigadores del\u00a0<a href=\"https:\/\/www.irbbarcelona.org\/es\/research\/translational-control-of-cell-cycle-and-differentiation\" target=\"_blank\" rel=\"noopener noreferrer\">Laboratorio de Control Translacional del Ciclo Celular y Diferenciaci\u00f3n<\/a>\u00a0del IRB Barcelona \u2013liderado\u00a0por\u00a0<a href=\"https:\/\/www.irbbarcelona.org\/es\/profile\/raul-mendez\" target=\"_blank\" rel=\"noopener noreferrer\">Ra\u00fal M\u00e9ndez<\/a>, experto en la familia de prote\u00ednas CPEB\u2013 revela la interacci\u00f3n entre las prote\u00ednas CPEB1 y Musashi1 (Msi1) en la regulaci\u00f3n de la traducci\u00f3n de\u00a0los ARNm.<br \/>\n\u00a0<\/p>\n<p>\u25ba <strong>M\u00e1s informaci\u00f3n:<\/strong> web del\u00a0<a href=\"https:\/\/www.irbbarcelona.org\/es\/news\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\" target=\"_blank\" rel=\"noopener noreferrer\">IRB Barcelona [+]<\/a><\/p>\n<p>\u25ba <strong>Art\u00edculo de referencia:<\/strong>\u00a0Laure Weill, Eul\u00e0lia Belloc, Chiara Lara Castellazzi and Ra\u00fal M\u00e9ndez. \u00ab<a href=\"https:\/\/www.nature.com\/nsmb\/journal\/vaop\/ncurrent\/full\/nsmb.3434.html\" target=\"_blank\" rel=\"noopener noreferrer\">Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs<\/a>\u00ab.\u00a0Nature Structural and Molecular Biology\u00a0(2017).\u00a0doi:10.1038\/nsmb.3434<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La revista\u00a0Nature Structural &amp; Molecular Biology\u00a0publica un estudio sobre la regulaci\u00f3n de la traducci\u00f3n del ARN mensajero, realizado por cient\u00edficos\u00a0del Instituto de Investigaci\u00f3n Biom\u00e9dica (IRB Barcelona) en el Parc Cient\u00edfic de Barcelona. El\u00a0estudio revela nuevos conocimientos sobre la regulaci\u00f3n de la traducci\u00f3n gen\u00e9tica \u2013un paso esencial en la regulaci\u00f3n del genoma\u2013 que\u00a0ayudar\u00e1n a los investigadores a comprender mejor procesos patol\u00f3gicos como el c\u00e1ncer.\u00a0<\/p>\n<p>\u00a0<\/p>\n","protected":false},"author":1,"featured_media":24731,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-38555","post","type-post","status-publish","format-standard","has-post-thumbnail","category-sin-categorizar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hacia una comprensi\u00f3n m\u00e1s profunda de la regulaci\u00f3n del genoma - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/es\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hacia una comprensi\u00f3n m\u00e1s profunda de la regulaci\u00f3n del genoma - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"La revista\u00a0Nature Structural &amp; Molecular Biology\u00a0publica un estudio sobre la regulaci\u00f3n de la traducci\u00f3n del ARN mensajero, realizado por cient\u00edficos\u00a0del Instituto de Investigaci\u00f3n Biom\u00e9dica (IRB Barcelona) en el Parc Cient\u00edfic de Barcelona. El\u00a0estudio revela nuevos conocimientos sobre la regulaci\u00f3n de la traducci\u00f3n gen\u00e9tica \u2013un paso esencial en la regulaci\u00f3n del genoma\u2013 que\u00a0ayudar\u00e1n a los investigadores a comprender mejor procesos patol\u00f3gicos como el c\u00e1ncer.\u00a0 \u00a0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pcb.ub.edu\/es\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\/\" \/>\n<meta property=\"og:site_name\" content=\"Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"article:published_time\" content=\"2017-07-19T23:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-16T15:20:33+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2017\/07\/16049215765fa928e8e49a7.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"527\" \/>\n\t<meta property=\"og:image:height\" content=\"480\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"adminpcb\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"adminpcb\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\\\/\"},\"author\":{\"name\":\"adminpcb\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\"},\"headline\":\"Hacia una comprensi\u00f3n m\u00e1s profunda de la regulaci\u00f3n del genoma\",\"datePublished\":\"2017-07-19T23:00:00+00:00\",\"dateModified\":\"2020-11-16T15:20:33+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\\\/\"},\"wordCount\":232,\"image\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.pcb.ub.edu\\\/wp-content\\\/uploads\\\/2017\\\/07\\\/16049215765fa928e8e49a7.jpeg\",\"articleSection\":[\"Sin categorizar\"],\"inLanguage\":\"es\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\\\/\",\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/hacia-una-comprension-mas-profunda-de-la-regulacion-del-genoma\\\/\",\"name\":\"Hacia una comprensi\u00f3n m\u00e1s profunda de la regulaci\u00f3n del genoma - 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