{"id":37637,"date":"2012-01-20T00:00:00","date_gmt":"2012-01-19T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/\/mejor-que-la-hormona-natural\/"},"modified":"2020-11-16T16:17:04","modified_gmt":"2020-11-16T15:17:04","slug":"mejor-que-la-hormona-natural","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/es\/mejor-que-la-hormona-natural\/","title":{"rendered":"Mejor que la hormona natural"},"content":{"rendered":"

\u00bb<\/p>\n

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\n\t\t\t\t\t\t<\/a>
\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div><\/div><\/div>\n

\t\t\tDesde hace varias d\u00e9cadas, la industria farmac\u00e9utica est\u00e1 interesada en obtener p\u00e9ptidos an\u00e1logos \u2013mol\u00e9culas similares con propiedades mejoradas- de la hormona natural somatostatina. Esta hormona y dos compuestos an\u00e1logos m\u00e1s -octreotide y lanreotide- se emplean como f\u00e1rmacos en el tratamiento de diversos tipos de neoplasias \u2013como el c\u00e1ncer de tiroides, p\u00e1ncreas o pr\u00f3stata-, en enfermedades relacionadas con la hormona del crecimiento \u2013por ejemplo en el gigantismo- y en hemorragias digestivas. <\/p>\n

\u00abEl uso de la hormona natural tiene dos inconvenientes: se degrada r\u00e1pidamente en el organismo, entre dos y tres minutos, y tiene un espectro de actividad muy amplio. Por eso es importante desarrollar compuestos m\u00e1s estables y m\u00e1s selectivos en su funci\u00f3n cuando se pretenden corregir ciertas enfermedades sin afectar al normal funcionamiento activado por la hormona natural.<\/p>\n

M\u00e1s informaci\u00f3n<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Un equipo de investigadores del IRB Barcelona, liderados por Antoni Riera (Universidad de Barcelona) y Maria Macias (Profesora de Investgaci\u00f3n ICREA), en colaboraci\u00f3n con la empresa BCN Peptides, ha dise\u00f1ado un p\u00e9ptido diez veces m\u00e1s estable en sangre que la hormona natural y m\u00e1s activo que los dos an\u00e1logos disponibles en el mercado. El \u00e9xito del dise\u00f1o se encuentra en la substituci\u00f3n de dos amino\u00e1cidos de la secuencia natural por dos amino\u00e1cidos no naturales. Angewandte Chemie, la segunda revista de qu\u00edmica en \u00edndice de impacto, ha publicado el art\u00edculo en edici\u00f3n avanzada digital y lo ha seleccionado como destacado para la portada de la edici\u00f3n de febrero. <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-37637","post","type-post","status-publish","format-standard","category-sin-categorizar"],"acf":[],"yoast_head":"\nMejor que la hormona natural - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/es\/mejor-que-la-hormona-natural\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mejor que la hormona natural - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"Un equipo de investigadores del IRB Barcelona, liderados por Antoni Riera (Universidad de Barcelona) y Maria Macias (Profesora de Investgaci\u00f3n ICREA), en colaboraci\u00f3n con la empresa BCN Peptides, ha dise\u00f1ado un p\u00e9ptido diez veces m\u00e1s estable en sangre que la hormona natural y m\u00e1s activo que los dos an\u00e1logos disponibles en el mercado. 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