{"id":88051,"date":"2023-09-20T12:26:27","date_gmt":"2023-09-20T10:26:27","guid":{"rendered":"https:\/\/www.pcb.ub.edu\/inbrain-achieves-fda-breakthrough-device-designation-for-its-smart-graphene-neural-platform\/"},"modified":"2023-09-21T13:22:52","modified_gmt":"2023-09-21T11:22:52","slug":"inbrain-achieves-fda-breakthrough-device-designation-for-its-smart-graphene-neural-platform","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/inbrain-achieves-fda-breakthrough-device-designation-for-its-smart-graphene-neural-platform\/","title":{"rendered":"InBrain achieves FDA Breakthrough Device Designation for its smart graphene-neural platform"},"content":{"rendered":"<p><strong><a href=\"https:\/\/www.pcb.ub.edu\/en\/empresa\/inbrain-neuroelectronics-sl\/\" target=\"_blank\" rel=\"noopener\">InBrain Neuroelectronics<\/a>, a health-tech company dedicated to developing the world\u2019s first smart graphene-neural platform, today announced that its intelligent network modulation system has been granted the Breakthrough Device Designation (BDD) from the U.S. Food &amp; Drug Administration (FDA) as an adjunctive therapy for treating Parkinson\u2019s disease. Thanks to this recognition, the company, headquartered in the Barcelona Science Park, will receive feedback throughout the regulatory process, as well as prioritized review by the agency.<\/strong><\/p>\n<p>The <a href=\"https:\/\/inbrain-neuroelectronics.com\/\" target=\"_blank\" rel=\"noopener\">InBrain<\/a>&#8216;s intelligent network modulation system harnesses the power of graphene, a two-dimensional material made of a lattice of carbon atoms only one atom thick. The thinnest material known, yet stronger than steel, graphene exhibits a unique combination of electrical and mechanical properties that makes it ideal for neurotechnology innovation. InBrain\u2019s neural platform technology enables ultra-high signal resolution at levels never achieved before and uses machine learning software that decodes therapy-specific biomarkers. This information is exploited to provide highly targeted and adaptive neuroelectronic treatments aimed at rebalancing pathological neural networks.<\/p>\n<div id=\"attachment_88037\" style=\"width: 710px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-88037\" class=\"wp-image-88037\" src=\"https:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2023\/09\/INBRAIN-Graphene-neural-interface-technology-.png\" alt=\"\" width=\"700\" height=\"358\" srcset=\"https:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2023\/09\/INBRAIN-Graphene-neural-interface-technology-.png 1047w, https:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2023\/09\/INBRAIN-Graphene-neural-interface-technology--300x154.png 300w, https:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2023\/09\/INBRAIN-Graphene-neural-interface-technology--1024x524.png 1024w, https:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2023\/09\/INBRAIN-Graphene-neural-interface-technology--768x393.png 768w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><p id=\"caption-attachment-88037\" class=\"wp-caption-text\">Inbrain&#8217;s graphene neural interface technology (Credits: InBrain Neuroelectronics).<\/p><\/div>\n<p>\u201cThis Breakthrough Device Designation from the FDA signifies the potential of the InBrain neural platform to further improve the lives of patients with Parkinson\u2019s disease,\u201d comments <strong>Dan Gnansia<\/strong>, InBrain Neuroelectronics Head of Clinical Affairs. \u201cWe look forward to working with the agency to help bring this important advance into clinical practice.\u201d<\/p>\n<p>The BDD recognizes devices that represent a major innovation or offer reasonable evidence of significant advantage over existing approved or cleared alternatives. It also expedites the development and FDA review of new devices with the potential to more effectively treat or diagnose life-threatening or irreversibly debilitating conditions.<\/p>\n<p>\u201cFrom the current available clinical brain interfaces, deep brain stimulation (DBS) is a successful therapy to treat Parkinson\u2019s disease. However, current leads have restrictions regarding their relatively large size and low density, limiting their precision for targeting of small deep structures such as the subthalamic nucleus (STN), and the spatial or signal resolution when sensing the local brain electrical activity,\u201d explains <strong>Helen Bronte Stewart<\/strong>, professor of neurology and neurological sciences at Stanford University School of Medicine. \u201cInBrain\u2019s new generation of ultrathin graphene-based high resolution interfaces and associated network platform may vastly improve the precision, efficiency and efficacy of DBS and closed-loop or adaptive modulation. The FDA Breakthrough Device designation is a statement to how this technology may be a paradigm shift in the scope of neuromodulation for people with Parkinson\u2019s disease and hopefully for other neuropsychiatric conditions in the future.\u201d<\/p>\n<p>Thanks to the FDA Breakthrough Device recognition of the InBrain system, the company will receive feedback throughout the regulatory process, as well as prioritized review by the agency.<\/p>\n<p>\u201cInBrain is dedicated to leveraging new discoveries in materials science and transforming them into safe and effective breakthrough therapy applications,\u201d adds <strong>Carolina Aguilar<\/strong>, InBrain Neuroelectronics CEO and co-founder \u201cWe anticipate developing our technology to treat other conditions affecting the central and peripheral nervous systems to make BCI technology relevant in neuro and bioelectronics.\u201d<\/p>\n<p><a href=\"https:\/\/www.inbrain-neuroelectronics.com\/\" target=\"_blank\" rel=\"noopener\">InBrain Neuroelectronics<\/a> was founded in 2020 as a spin-off of the Catalan Institute of Nanoscience and Nanotechnology (<a href=\"https:\/\/icn2.cat\/en\/\" target=\"_blank\" rel=\"noopener\">ICN2<\/a>) and\u00a0<a href=\"https:\/\/www.icrea.cat\/es\" target=\"_blank\" rel=\"noopener\">ICREA<\/a>, with the participation of the Institute of Microelectronics of Barcelona (<a href=\"https:\/\/www.imb-cnm.csic.es\/ca\/linstitut\" target=\"_blank\" rel=\"noopener\">IMB-CNM-CSIC<\/a>). In addition to <strong>Carolina Aguilar,<\/strong> other of its founders are ICREA Prof. <strong>Jose A. Garrido<\/strong>, <a href=\"https:\/\/icn2.cat\/en\/advanced-electronic-materials-and-devices-group\" target=\"_blank\" rel=\"noopener\">Advanced Electronic Materials and Devices<\/a>&#8216;s group leader at ICN2 (Barcelona, Spain); Prof.<strong> Kostas Kostarelos<\/strong>, group leader at ICN2 and chair of Nanomedicine at the University of Manchester (UK), and Dr<strong> Anton Guimer\u00e0<\/strong>, staff researcher at IMB-CNM-CSIC (Barcelona, Spain).<\/p>\n<p>InBrain develops semiconductors derived brain computer interface (BCI) technology that applied in neuromodulation is designed to decode and modulate brain activity in high resolution, using artificial intelligence to trigger adaptive responses for personalized neurological treatment in Parkinson\u2019s disease, epilepsy and speech impairment.<\/p>\n<p><strong>\u00bb <a href=\"https:\/\/www.pcb.ub.edu\/en\/icn2-spin-off-inbrain-pioneer-in-bioelectronics-moves-into-barcelona-science-park\/\" target=\"_blank\" rel=\"noopener\">Related news [+]<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>InBrain Neuroelectronics, a health-tech company dedicated to developing the world\u2019s first smart graphene-neural platform, today announced that its intelligent network modulation system has been granted the Breakthrough Device Designation (BDD)&#8230;<\/p>\n","protected":false},"author":14,"featured_media":88031,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-88051","post","type-post","status-publish","format-standard","has-post-thumbnail","category-business"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - 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