{"id":67479,"date":"2021-10-26T12:18:23","date_gmt":"2021-10-26T10:18:23","guid":{"rendered":"https:\/\/www.pcb.ub.edu\/chemotargets-and-the-crg-ally-to-accelerate-the-development-of-new-treatments\/"},"modified":"2021-11-26T12:24:25","modified_gmt":"2021-11-26T11:24:25","slug":"chemotargets-and-the-crg-ally-to-accelerate-the-development-of-new-treatments","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/chemotargets-and-the-crg-ally-to-accelerate-the-development-of-new-treatments\/","title":{"rendered":"Chemotargets and CRG ally to accelerate the development of new treatments"},"content":{"rendered":"

Drug discovery biotech firm Chemotargets<\/a>, based in the Barcelona Science Park, and the Centre for Genomic Regulation (CRG)<\/a> have signed a strategic agreement to accelerate the development of new targeted therapies that respond to unmet clinical needs in different fields including cancer.<\/strong><\/p>\n

The development of new treatments for diseases requires the identification of potential targets \u2013 for example proteins or enzymes \u2013 that are critical for the onset and progression of the disease. After finding a candidate, researchers need to screen thousands of potential molecules that might interfere with the target and test for their effectiveness and safety. This \u2018bench to bedside\u2019 process is expensive and takes many years of research before benefiting patients.<\/p>\n

Recent technological advances in artificial intelligence, advanced computing and mass-scale data analysis is accelerating the drug development process, sometimes reducing the timescale of the process by years.<\/p>\n

Chemotargets, a global leader in the field, develops computational platforms for the design, optimization and safety evaluation of drugs. The biotech firm\u2019s cutting-edge computational technologies can rapidly design potential new drug candidates for therapeutic targets that are difficult to treat and for which no identified drugs currently exist.<\/p>\n

The new partnership will leverage the CRG\u2019s fundamental knowledge on the complexity of life, as well as its expertise in identifying potential new therapeutic targets in emerging fields of cancer biology. 70% of the translational projects making up the portfolio of the CRG\u2019s Technology and Business Development Office (TBDO) focus on the validation of new therapeutic targets for the treatment of different diseases such as cancer, fibrosis, eye diseases, blood diseases or diseases that cause inflammation.<\/p>\n

The first project under the agreement involves a new target identified by Dr Isabelle Vernos<\/strong>\u2019 group in the CRG\u2019s Cell and Developmental Biology research programme. The Vernos group has world-leading expertise on fundamental biological processes such as cell division with a focus on the mechanisms of spindle assembly and chromosome segregation fidelity, processes that when dysregulated can be associated with infertility and cancer.<\/p>\n

\u201cThe CRG\u2019s strengths lie in our profound understanding of fundamental aspects of human biology, our world-leading expertise in the design and engineering of proteins, and our state-of-the-art technological platforms in genomics, proteomics, screening, tissue engineering and organoids. Partnering with a high-profile company like Chemotargets will be a vital boost to leverage our know-how for the benefit of patients in need,\u201d says Dr Luis\u00a0 Serrano<\/strong>, director of the CRG.<\/p>\n

“We welcome this collaboration and look forward to working with the CRG on several levels.\u00a0 In addition to world-class fundamental biology, the infrastructure to rapidly design medications specific for the phenotype and genotype of both disease and patient in collaboration with the CRG brings a critical new dimension to Chemotargets\u2019 growing internal pipeline,”\u00a0Dr Scott Boyer<\/strong>, Chemotargets CEO.<\/p>\n","protected":false},"excerpt":{"rendered":"

Drug discovery biotech firm Chemotargets, based in the Barcelona Science Park, and the Centre for Genomic Regulation (CRG) have signed a strategic agreement to accelerate the development of new targeted…<\/p>\n","protected":false},"author":4,"featured_media":67474,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-67479","post","type-post","status-publish","format-standard","has-post-thumbnail","category-business"],"acf":[],"yoast_head":"\nChemotargets and CRG ally to accelerate the development of new treatments - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/en\/chemotargets-and-the-crg-ally-to-accelerate-the-development-of-new-treatments\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemotargets and CRG ally to accelerate the development of new treatments - 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