{"id":59948,"date":"2021-02-16T10:09:23","date_gmt":"2021-02-16T09:09:23","guid":{"rendered":"https:\/\/www.pcb.ub.edu\/oncoheroes-and-shepherd-have-entered-into-a-partnership-to-advance-in-innovative-therapies-for-rare-cancers\/"},"modified":"2024-05-16T17:01:23","modified_gmt":"2024-05-16T15:01:23","slug":"oncoheroes-and-shepherd-have-entered-into-a-partnership-to-advance-in-innovative-therapies-for-rare-cancers","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/oncoheroes-and-shepherd-have-entered-into-a-partnership-to-advance-in-innovative-therapies-for-rare-cancers\/","title":{"rendered":"Oncoheroes and Shepherd have entered into a partnership to advance in innovative therapies for rare cancers"},"content":{"rendered":"<p><strong><a href=\"https:\/\/www.pcb.ub.edu\/en\/empresa\/oncoheroes-biosciencies\/\" target=\"_blank\" rel=\"noopener noreferrer\">Oncoheroes Biosciences<\/a>, focused on advancing new therapies for childhood cancer, announces\u00a0 a partnership with the North American company <a href=\"https:\/\/shepherd.bio\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"hiddenSpellError\">Shepherd<\/span>\u00a0<span class=\"hiddenSpellError\">Therapeutics<\/span><\/a> to collaborate in the discovery, development and commercialization of innovative drug products for rare oncology indications. The startup \u2013co-founded in 2017 in Boston by the Catalan entrepreneur Ricardo Garcia and the Italian scientist Cesare Spadoni, two parents touched by childhood cancer\u2013 has the European headquarters at the Barcelona Science Park.<\/strong><\/p>\n<p>Oncoheroes and <span class=\"hiddenSpellError\">Shepherd<\/span>\u2019s collaboration advances a paradigm change in drug development for rare cancers. The companies will use Delve, <span class=\"hiddenSpellError\">S<\/span><span class=\"hiddenSpellError\">hepherd<\/span>\u2019s next-generation, precision-oncology platform that integrates bioinformatics, machine learning and mathematics, to unveil unprecedented insights into rare cancers, including childhood cancer.<\/p>\n<p>Delve enables the companies to move beyond a single target-based approach to identify all of the primary mechanisms of action responsible for drug response and resistance within the human transcriptome.<\/p>\n<p>The companies\u2019 first project of the collaboration will identify additional pediatric and rare adult indications for Oncoheroes\u2019 lead asset: Volasertib.<\/p>\n<p>Volasertib is an inhibitor of Polo-like-kinase 1 (PLK1), an enzyme known to be involved in disease progression in a number of cancers. Volasertib has recently been granted Rare Pediatric Disease Designation (RPDD) and Orphan Drug Designation (ODD) by the FDA for the treatment of rhabdomyosarcoma, the most common soft tissue sarcoma in children and young adults, representing 3-4% of all childhood cancers.<\/p>\n<p>\u201cGetting a diagnosis of cancer as a child should not be a death sentence, yet too many lives are being lost or diminished because of a dearth of pediatric cancer research and treatments\u201d, says David Hysong, CEO of <span class=\"hiddenSpellError\">S<\/span><span class=\"hiddenSpellError\">hepherd<\/span>. \u201dOur companies are coming together in hope and in action, leveraging the full extent of our combined technology, experience, and expertise to help save lives&#8221;.<\/p>\n<p>\u201cWe are excited about this partnership between two mission-driven companies determined to address high unmet medical needs in the rare oncology space. We are confident that <span class=\"hiddenSpellError\">S<\/span><span class=\"hiddenSpellError\">hepherd<\/span>\u2019s technology, combined with Oncoheroes\u2019 expertise in the pediatric oncology space, will deliver new therapeutics options to children and adolescents with cancer,\u201d states Ricardo Garcia, CEO of Oncoheroes.<\/p>\n<p><strong>\u00a0\u00bb For further information: <a href=\"https:\/\/oncoheroes.com\/press-releases-content\/2021\/2\/12\/shepherd-therapeutics-and-oncoheroes-biosciences-to-partner-for-the-discovery-development-and-commercialization-of-oncology-therapeutics-for-rare-cancers\" target=\"_blank\" rel=\"noopener noreferrer\">Oncoheroes website [+]<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Oncoheroes Biosciences, focused on advancing new therapies for childhood cancer, announces\u00a0 a partnership with the North American company Shepherd\u00a0Therapeutics to collaborate in the discovery, development and commercialization of innovative drug&#8230;<\/p>\n","protected":false},"author":14,"featured_media":59937,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-59948","post","type-post","status-publish","format-standard","has-post-thumbnail","category-business"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - 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