{"id":50297,"date":"2019-03-04T00:00:00","date_gmt":"2019-03-03T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/a-new-technique-allows-researchers-to-focus-the-action-of-drugs-via-infrared-light\/"},"modified":"2019-03-04T00:00:00","modified_gmt":"2019-03-03T23:00:00","slug":"a-new-technique-allows-researchers-to-focus-the-action-of-drugs-via-infrared-light","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/a-new-technique-allows-researchers-to-focus-the-action-of-drugs-via-infrared-light\/","title":{"rendered":"A new technique allows researchers to focus the action of drugs via infrared light"},"content":{"rendered":"<p>Having absolute control of the activity of a molecule in an organism. Deciding when, where and how a drug is activated. These are some of the goals expected to be reached with the so-called photoswitchable molecules, compounds that, in the presence of certain light waves, change their properties. Today, thanks to the results of a study led by IBEC\u00a0together with UAB, the scientific community is one step closer to achieving this objective.<\/p>\n<p>Using pulsed infrared light lasers, scientists have managed, for the first time, to activate molecules located inside neural tissue, with an efficiency of almost 100%. \u2018It\u2019s a development that opens the door to a large number of applications. From drugs that only act at the point of our body that is illuminated and are therefore free from unwanted side-effects in other regions, to the spatial and temporal control of any protein whose function we want to study in the context of an organism\u2019, says Pau Gorostiza, ICREA research professor and head of the Nanoprobes and Nanoswitches Group at IBEC.\u00a0<\/p>\n<p><strong>\u25ba Reference article:<\/strong>\u00a0Gisela Cabr\u00e9, Aida Garrido-Charles, Miquel Moreno, Miquel Bosch, Montserrat Porta-de-la-Riva, Michael Krieg, Marta Gasc\u00f3n-Moya, N\u00faria Camarero, Ricard Gelabert, Jos\u00e9 M. Lluch, F\u00e9lix Busqu\u00e9, Jordi Hernando, Pau Gorostiza &amp; Ramon Alib\u00e9s. &#8220;<a href=\"https:\/\/www.nature.com\/articles\/s41467-019-08796-9\" rel=\"noopener noreferrer\" style=\"font-weight: 200\" target=\"_blank\">Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation<\/a>&#8220;. Nature Communications volume 10, Article number: 907 (2019).<\/p>\n<p>\u25ba <strong>More information<\/strong>: <a href=\"http:\/\/www.ibecbarcelona.eu\/a-new-technique-allows-researchers-to-focus-the-action-of-drugs-via-infrared-light\/\" target=\"_blank\" rel=\"noopener noreferrer\">IBEC website\u00a0[+]<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A scientific team led by the Institute for Bioengineering of Catalonia (<a href=\"http:\/\/www.pcb.ub.edu\/portal\/en\/cerca?p_p_id=cercador_WAR_empleatsempresesportlet&amp;p_p_lifecycle=0&amp;p_p_state=maximized&amp;p_p_mode=view&amp;p_p_col_id=column-1&amp;p_p_col_count=1&amp;_cercador_WAR_empleatsempresesportlet_jspPage=%2Fhtml%2Fcommon%2Fdetall-empresa.jsp&amp;_cercador_WAR_empleatsempresesportlet_empresaId=ENT_000134&amp;_cercador_WAR_empleatsempresesportlet_redirect=%2Fportal%2Fca%2Fcerca%3Fp_p_id%3Dcercador_WAR_empleatsempresesportlet%26p_p_lifecycle%3D0%26p_p_mode%3Dview%26_cercador_WAR_empleatsempresesportlet_keywords%3Dibec%26_cercador_WAR_empleatsempresesportlet_tab%3D1\" target=\"_blank\" rel=\"noopener noreferrer\">IBEC<\/a>), based at the Barcelona Science Park, and the Universitat Aut\u00f2noma de Barcelona (UAB)manages to efficiently activate molecules located inside cell tissues using two-photon excitation of with infrared light lasers. The study has recently been published in the journal\u00a0Nature Communications.<\/p>\n<p>\u00a0<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-50297","post","type-post","status-publish","format-standard","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A new technique allows researchers to focus the action of drugs via infrared light - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/en\/a-new-technique-allows-researchers-to-focus-the-action-of-drugs-via-infrared-light\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new technique allows researchers to focus the action of drugs via infrared light - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"A scientific team led by the Institute for Bioengineering of Catalonia (IBEC), based at the Barcelona Science Park, and the Universitat Aut\u00f2noma de Barcelona (UAB)manages to efficiently activate molecules located inside cell tissues using two-photon excitation of with infrared light lasers. 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