{"id":48318,"date":"2013-02-19T00:00:00","date_gmt":"2013-02-18T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/"},"modified":"2020-11-18T14:53:01","modified_gmt":"2020-11-18T13:53:01","slug":"discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/","title":{"rendered":"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene"},"content":{"rendered":"

”<\/p>\n

\n
\n
\n\t\t\t\t\t\t<\/a>
\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div><\/div><\/div>\n

\t\t\tNMR techniques, essential for this research. were carried out in the Singular Scientific and Technological Facility of the University of Barcelona, located at the Barcelona Science Park (PCB). Margarida Gair\u00ed, from the Scientific and Technological Centers of the UB, and some researchers from the IRB also participated in the study. All participating groups are affiliated with the Barcelona Knowledge Campus, a campus of international excellence. <\/p>\n

According to Miquel Pons, leader of the Biomolecular Nuclear Magnetic Resonance (NMR) Research Group, affiliated with the Department of Organic Chemistry of the UB, “the discovery of a new regulatory mechanism in such a relevant and extensively studied protein proves the importance of original approaches based on molecular structure to find new biological activities and suggest new strategies in the fight against cancer”. <\/p>\n

For further information [+]<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

The c-Src protein is the cellular form associated to the first oncogene (a mutant protein which turns healthy cells into carcinogenic ones) discovered in the Rous sarcoma virus more than one hundred years ago and which has been extensively studied since the 1980s. The oncogenic character of c-Src results mainly from incorrect regulation of this protein. A research, led by UB professor Miquel Pons that has been just published on Scientific Reports, has discovered a new regulation region of this protein that, when modified, can affect the survival of the <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-48318","post","type-post","status-publish","format-standard","category-uncategorized"],"acf":[],"yoast_head":"\nDiscovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"The c-Src protein is the cellular form associated to the first oncogene (a mutant protein which turns healthy cells into carcinogenic ones) discovered in the Rous sarcoma virus more than one hundred years ago and which has been extensively studied since the 1980s. The oncogenic character of c-Src results mainly from incorrect regulation of this protein. A research, led by UB professor Miquel Pons that has been just published on Scientific Reports, has discovered a new regulation region of this protein that, when modified, can affect the survival of the\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/\" \/>\n<meta property=\"og:site_name\" content=\"Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"article:published_time\" content=\"2013-02-18T23:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-18T13:53:01+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1361263232117.jpg\" \/>\n<meta name=\"author\" content=\"adminpcb\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"adminpcb\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/\"},\"author\":{\"name\":\"adminpcb\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\"},\"headline\":\"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene\",\"datePublished\":\"2013-02-18T23:00:00+00:00\",\"dateModified\":\"2020-11-18T13:53:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/\"},\"wordCount\":147,\"image\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/www.pcb.ub.edu\\\/wp-content\\\/uploads\\\/2020\\\/11\\\/1361263232117.jpg\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/\",\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/\",\"name\":\"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene - Parc Cient\u00edfic de Barcelona\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/www.pcb.ub.edu\\\/wp-content\\\/uploads\\\/2020\\\/11\\\/1361263232117.jpg\",\"datePublished\":\"2013-02-18T23:00:00+00:00\",\"dateModified\":\"2020-11-18T13:53:01+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#primaryimage\",\"url\":\"http:\\\/\\\/www.pcb.ub.edu\\\/wp-content\\\/uploads\\\/2020\\\/11\\\/1361263232117.jpg\",\"contentUrl\":\"http:\\\/\\\/www.pcb.ub.edu\\\/wp-content\\\/uploads\\\/2020\\\/11\\\/1361263232117.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#website\",\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/\",\"name\":\"Parc Cient\u00edfic de Barcelona\",\"description\":\"Universitat de Barcelona\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\",\"name\":\"adminpcb\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g\",\"caption\":\"adminpcb\"},\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/author\\\/adminpcb\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene - Parc Cient\u00edfic de Barcelona","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/","og_locale":"en_US","og_type":"article","og_title":"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene - Parc Cient\u00edfic de Barcelona","og_description":"The c-Src protein is the cellular form associated to the first oncogene (a mutant protein which turns healthy cells into carcinogenic ones) discovered in the Rous sarcoma virus more than one hundred years ago and which has been extensively studied since the 1980s. The oncogenic character of c-Src results mainly from incorrect regulation of this protein. A research, led by UB professor Miquel Pons that has been just published on Scientific Reports, has discovered a new regulation region of this protein that, when modified, can affect the survival of the","og_url":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/","og_site_name":"Parc Cient\u00edfic de Barcelona","article_published_time":"2013-02-18T23:00:00+00:00","article_modified_time":"2020-11-18T13:53:01+00:00","og_image":[{"url":"http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1361263232117.jpg","type":"","width":"","height":""}],"author":"adminpcb","twitter_card":"summary_large_image","twitter_misc":{"Written by":"adminpcb","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#article","isPartOf":{"@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/"},"author":{"name":"adminpcb","@id":"https:\/\/www.pcb.ub.edu\/es\/#\/schema\/person\/d13cab05cd0a75b17fddca8496481021"},"headline":"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene","datePublished":"2013-02-18T23:00:00+00:00","dateModified":"2020-11-18T13:53:01+00:00","mainEntityOfPage":{"@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/"},"wordCount":147,"image":{"@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#primaryimage"},"thumbnailUrl":"http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1361263232117.jpg","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/","url":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/","name":"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene - Parc Cient\u00edfic de Barcelona","isPartOf":{"@id":"https:\/\/www.pcb.ub.edu\/es\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#primaryimage"},"image":{"@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#primaryimage"},"thumbnailUrl":"http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1361263232117.jpg","datePublished":"2013-02-18T23:00:00+00:00","dateModified":"2020-11-18T13:53:01+00:00","author":{"@id":"https:\/\/www.pcb.ub.edu\/es\/#\/schema\/person\/d13cab05cd0a75b17fddca8496481021"},"breadcrumb":{"@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#primaryimage","url":"http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1361263232117.jpg","contentUrl":"http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1361263232117.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.pcb.ub.edu\/en\/discovered-a-new-regulatory-mechanism-of-c-src-the-human-protein-bound-to-the-oldest-known-oncogene\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.pcb.ub.edu\/en\/"},{"@type":"ListItem","position":2,"name":"Discovered a new regulatory mechanism of c-Src, the human protein bound to the oldest known oncogene"}]},{"@type":"WebSite","@id":"https:\/\/www.pcb.ub.edu\/es\/#website","url":"https:\/\/www.pcb.ub.edu\/es\/","name":"Parc Cient\u00edfic de Barcelona","description":"Universitat de Barcelona","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pcb.ub.edu\/es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pcb.ub.edu\/es\/#\/schema\/person\/d13cab05cd0a75b17fddca8496481021","name":"adminpcb","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g","caption":"adminpcb"},"url":"https:\/\/www.pcb.ub.edu\/en\/author\/adminpcb\/"}]}},"_links":{"self":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts\/48318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/comments?post=48318"}],"version-history":[{"count":1,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts\/48318\/revisions"}],"predecessor-version":[{"id":52412,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts\/48318\/revisions\/52412"}],"wp:attachment":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/media?parent=48318"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/categories?post=48318"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/tags?post=48318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}