{"id":47367,"date":"2011-07-22T00:00:00","date_gmt":"2011-07-21T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/new-proteins-required-for-correct-embryonic-development\/"},"modified":"2020-11-18T14:51:28","modified_gmt":"2020-11-18T13:51:28","slug":"new-proteins-required-for-correct-embryonic-development","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/new-proteins-required-for-correct-embryonic-development\/","title":{"rendered":"New proteins required for correct embryonic development"},"content":{"rendered":"

”<\/p>\n

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\t\t\tThe proteins p38\u03b1 and p38\u03b2 are key components of cells that control essential functions such as cell proliferation, differentiation and death. This would explain that a defect in these proteins causes alterations in cell regulation, which may lead to the development of tumors. Although many studies have characterized these proteins, few genetic studies have been done on their function “in vivo” in mammals. <\/p>\n

The study has been conducted mainly by Dr. Iv\u00e1n del Barco Barrantes, first author of the article. Using gene manipulation, he has managed to deleted p38\u03b1 and p38\u03b2 from the mouse. This new approach has allowed these researchers to study for the first time the role of those proteins as a whole rather than the separate function of each, which is what has been done until now. <\/p>\n

More information<\/a> <\/p>\n","protected":false},"excerpt":{"rendered":"

Researchers at IRB Barcelona \u2013based in the Barcelona Scientific Park\u2013 discover new roles of p38 proteins during embryonic development. The study, headed by ICREA Research Professor and BBVA Foundation Cancer Research Professor \u00c1ngel Rodr\u00edguez Nebreda, has been published this week in the online version of Proceedings of the National Academy of Sciences of the United States of America (PNAS). <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-47367","post","type-post","status-publish","format-standard","category-uncategorized"],"acf":[],"yoast_head":"\nNew proteins required for correct embryonic development - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/en\/new-proteins-required-for-correct-embryonic-development\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New proteins required for correct embryonic development - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"Researchers at IRB Barcelona \u2013based in the Barcelona Scientific Park\u2013 discover new roles of p38 proteins during embryonic development. 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