{"id":47288,"date":"2011-06-14T00:00:00","date_gmt":"2011-06-13T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/the-fight-against-the-toxic-aggregation-of-proteins-according-to-darwin\/"},"modified":"2020-11-18T14:51:21","modified_gmt":"2020-11-18T13:51:21","slug":"the-fight-against-the-toxic-aggregation-of-proteins-according-to-darwin","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/the-fight-against-the-toxic-aggregation-of-proteins-according-to-darwin\/","title":{"rendered":"The fight against the toxic aggregation of proteins according to Darwin"},"content":{"rendered":"<p>&#8221;<\/p>\n<div class=\"col-sm-6 detall-noticia-imatges\">\n<div class=\"row\">\n<div class=\"item active one-image\">\n\t\t\t\t\t\t<a class=\"icon-search\" href='http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1308237523890.jpg'><\/a><br \/>\n\t\t\t\t\t\t<img src='http:\/\/www.pcb.ub.edu\/wp-content\/uploads\/2020\/11\/1308237523890.jpg' \/>\n\t\t\t\t\t<\/div><\/div><\/div>\n<p>\t\t\tAccording to these scientists, these results would explain the greater presence of these bonds in proteins secreted extracellularly, an environment in which they aggregate more easily. Involving collaboration with researchers at the &#8220;Centre de Regulaci\u00f3 Gen\u00f2mica de Barcelona&#8221;, the University of Cambridge (UK) and the University of Li\u00e8ge (Belgium), the study has come out in Angewandte Chemie, one of the most prestigious international journal of chemistry.  <\/p>\n<p> <a>More information<\/a> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers headed by Xavier Salvatella, ICREA researcher with the joint program between the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Supercomputing Center (BSC), have discovered that certain bonds that keep proteins folded, called disulfide bridges, induce the formation of protein aggregates that are more stable and less toxic for cells than those that don&#8217;t have them.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-47288","post","type-post","status-publish","format-standard","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - 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