{"id":47103,"date":"2011-03-18T00:00:00","date_gmt":"2011-03-17T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/"},"modified":"2020-11-18T14:51:04","modified_gmt":"2020-11-18T13:51:04","slug":"stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/","title":{"rendered":"Stem cells may be key to understanding the origins of colon cancer and detecting relapse"},"content":{"rendered":"<p>The results of the study, published online this week in Cell Stem Cell, offer new possibilities for diagnosing and treating the disease. The study conducted by Anna Merlos-Su\u00e1rez and other researchers in Batlle&#8217;s team has uncovered a close relation between intestinal stem cells (non-specialised cells that generate all cells within the intestine) and colorectal cancer.  <\/p>\n<p> The researchers compared genes that are activated in cells from a healthy intestine \u2013 both stem cells and specialised cells \u2013 with the genes that are activated in tumour cells taken from patients. &#8220;Our results show that patients with colon cancer have a set of genes activated that is very similar to the set activated in stem cells. The more genes they have activated in common, the more likely it is that the patient&#8217;s cancer will spread and relapse.  <\/p>\n<p> One of the biggest hurdles that oncologists face is a lack of tools to identify which patients have a higher risk of relapse. Discovering a close relation between intestinal stem cells and the propagation of cancer is a clear breakthrough in this respect. The hypothesis that colorectal cancer requires a specific type of cell to develop and thrive has also been demonstrated in other types of cancer, including gliomas, some types of lymphoma or breast cancer. This finding opens the door for the development of treaments aimed at these new targets in the fight against cancer: tumour stem cells.  <\/p>\n<p> <a href=\"http:\/\/www.irbbarcelona.org\/index.php\/en\/news\/irb-news\/scientific\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\" class=\"email\">More information<\/a>  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Colorectal cancer cells trigger a set of genes similar to those found in intestinal stem cells, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have found. The team of researchers, led by ICREA researcher Eduard Batlle, propose that patients with colorectal cancer undergo genetic tests of their intestinal epithelium in order to predict a higher risk of relapse. <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-47103","post","type-post","status-publish","format-standard","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Stem cells may be key to understanding the origins of colon cancer and detecting relapse - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stem cells may be key to understanding the origins of colon cancer and detecting relapse - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"Colorectal cancer cells trigger a set of genes similar to those found in intestinal stem cells, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have found. The team of researchers, led by ICREA researcher Eduard Batlle, propose that patients with colorectal cancer undergo genetic tests of their intestinal epithelium in order to predict a higher risk of relapse.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/\" \/>\n<meta property=\"og:site_name\" content=\"Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"article:published_time\" content=\"2011-03-17T23:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-18T13:51:04+00:00\" \/>\n<meta name=\"author\" content=\"adminpcb\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"adminpcb\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/\"},\"author\":{\"name\":\"adminpcb\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\"},\"headline\":\"Stem cells may be key to understanding the origins of colon cancer and detecting relapse\",\"datePublished\":\"2011-03-17T23:00:00+00:00\",\"dateModified\":\"2020-11-18T13:51:04+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/\"},\"wordCount\":249,\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/\",\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/\",\"name\":\"Stem cells may be key to understanding the origins of colon cancer and detecting relapse - Parc Cient\u00edfic de Barcelona\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#website\"},\"datePublished\":\"2011-03-17T23:00:00+00:00\",\"dateModified\":\"2020-11-18T13:51:04+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Stem cells may be key to understanding the origins of colon cancer and detecting relapse\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#website\",\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/\",\"name\":\"Parc Cient\u00edfic de Barcelona\",\"description\":\"Universitat de Barcelona\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\",\"name\":\"adminpcb\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g\",\"caption\":\"adminpcb\"},\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/author\\\/adminpcb\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Stem cells may be key to understanding the origins of colon cancer and detecting relapse - Parc Cient\u00edfic de Barcelona","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/","og_locale":"en_US","og_type":"article","og_title":"Stem cells may be key to understanding the origins of colon cancer and detecting relapse - Parc Cient\u00edfic de Barcelona","og_description":"Colorectal cancer cells trigger a set of genes similar to those found in intestinal stem cells, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have found. The team of researchers, led by ICREA researcher Eduard Batlle, propose that patients with colorectal cancer undergo genetic tests of their intestinal epithelium in order to predict a higher risk of relapse.","og_url":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/","og_site_name":"Parc Cient\u00edfic de Barcelona","article_published_time":"2011-03-17T23:00:00+00:00","article_modified_time":"2020-11-18T13:51:04+00:00","author":"adminpcb","twitter_card":"summary_large_image","twitter_misc":{"Written by":"adminpcb","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/#article","isPartOf":{"@id":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/"},"author":{"name":"adminpcb","@id":"https:\/\/www.pcb.ub.edu\/es\/#\/schema\/person\/d13cab05cd0a75b17fddca8496481021"},"headline":"Stem cells may be key to understanding the origins of colon cancer and detecting relapse","datePublished":"2011-03-17T23:00:00+00:00","dateModified":"2020-11-18T13:51:04+00:00","mainEntityOfPage":{"@id":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/"},"wordCount":249,"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/","url":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/","name":"Stem cells may be key to understanding the origins of colon cancer and detecting relapse - Parc Cient\u00edfic de Barcelona","isPartOf":{"@id":"https:\/\/www.pcb.ub.edu\/es\/#website"},"datePublished":"2011-03-17T23:00:00+00:00","dateModified":"2020-11-18T13:51:04+00:00","author":{"@id":"https:\/\/www.pcb.ub.edu\/es\/#\/schema\/person\/d13cab05cd0a75b17fddca8496481021"},"breadcrumb":{"@id":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pcb.ub.edu\/en\/stem-cells-may-be-key-to-understanding-the-origins-of-colon-cancer-and-detecting-relapse\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.pcb.ub.edu\/en\/"},{"@type":"ListItem","position":2,"name":"Stem cells may be key to understanding the origins of colon cancer and detecting relapse"}]},{"@type":"WebSite","@id":"https:\/\/www.pcb.ub.edu\/es\/#website","url":"https:\/\/www.pcb.ub.edu\/es\/","name":"Parc Cient\u00edfic de Barcelona","description":"Universitat de Barcelona","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pcb.ub.edu\/es\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pcb.ub.edu\/es\/#\/schema\/person\/d13cab05cd0a75b17fddca8496481021","name":"adminpcb","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/41ad0fab4bb3bf5348b0af9612159cfd93173a57bbca98fecb50fa6f3ab97d28?s=96&d=mm&r=g","caption":"adminpcb"},"url":"https:\/\/www.pcb.ub.edu\/en\/author\/adminpcb\/"}]}},"_links":{"self":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts\/47103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/comments?post=47103"}],"version-history":[{"count":1,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts\/47103\/revisions"}],"predecessor-version":[{"id":51949,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/posts\/47103\/revisions\/51949"}],"wp:attachment":[{"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/media?parent=47103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/categories?post=47103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pcb.ub.edu\/en\/wp-json\/wp\/v2\/tags?post=47103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}