{"id":46771,"date":"2010-09-22T00:00:00","date_gmt":"2010-09-21T23:00:00","guid":{"rendered":"http:\/\/www.pcb.ub.edu\/first-observation-of-the-folding-of-a-nucleic-acid\/"},"modified":"2020-11-18T14:50:31","modified_gmt":"2020-11-18T13:50:31","slug":"first-observation-of-the-folding-of-a-nucleic-acid","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/first-observation-of-the-folding-of-a-nucleic-acid\/","title":{"rendered":"First observation of the folding of a nucleic acid"},"content":{"rendered":"<p>The study havsbeen published in the world&#8217;s leading chemistry magazine, Angewandte Chemie, and his results has far-reaching implications not only because it represents a new milestone in the theoretical study of nucleic acids&#8217; folding, but also it is of great importance for the design of new therapeutic strategies based on oligonucleotides. This is the case, e.g., for RNA interference based treatments, which will help to fight complex diseases such as cancer.  <\/p>\n<p> <a>Per a m\u00e9s informaci\u00f3<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Since the elucidation of the three-dimensional structure of DNA (the molecule that carries all genetic information) by Watson and Crick, scientists have strived to decipher the hidden code that determines the evolution of the spatial arrangement of these molecules towards their functional native state. The researchers Modesto Orozco, Life Sciences Director of the Barcelona Supercomputing Center and responsible of the Molecular Modelling and Bioinformatics group at the Institute for Research in Biomedicine (IRB Barcelona), and Guillem Portella, postdoctoral researcher of his group, have been able to describe for the first time the folding process of a small DNA hairpin in water and with atomic resolution. <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-46771","post","type-post","status-publish","format-standard","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>First observation of the folding of a nucleic acid - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/en\/first-observation-of-the-folding-of-a-nucleic-acid\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"First observation of the folding of a nucleic acid - Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"og:description\" content=\"Since the elucidation of the three-dimensional structure of DNA (the molecule that carries all genetic information) by Watson and Crick, scientists have strived to decipher the hidden code that determines the evolution of the spatial arrangement of these molecules towards their functional native state. The researchers Modesto Orozco, Life Sciences Director of the Barcelona Supercomputing Center and responsible of the Molecular Modelling and Bioinformatics group at the Institute for Research in Biomedicine (IRB Barcelona), and Guillem Portella, postdoctoral researcher of his group, have been able to describe for the first time the folding process of a small DNA hairpin in water and with atomic resolution.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pcb.ub.edu\/en\/first-observation-of-the-folding-of-a-nucleic-acid\/\" \/>\n<meta property=\"og:site_name\" content=\"Parc Cient\u00edfic de Barcelona\" \/>\n<meta property=\"article:published_time\" content=\"2010-09-21T23:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-18T13:50:31+00:00\" \/>\n<meta name=\"author\" content=\"adminpcb\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"adminpcb\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/first-observation-of-the-folding-of-a-nucleic-acid\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/first-observation-of-the-folding-of-a-nucleic-acid\\\/\"},\"author\":{\"name\":\"adminpcb\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/es\\\/#\\\/schema\\\/person\\\/d13cab05cd0a75b17fddca8496481021\"},\"headline\":\"First observation of the folding of a nucleic acid\",\"datePublished\":\"2010-09-21T23:00:00+00:00\",\"dateModified\":\"2020-11-18T13:50:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/first-observation-of-the-folding-of-a-nucleic-acid\\\/\"},\"wordCount\":86,\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/first-observation-of-the-folding-of-a-nucleic-acid\\\/\",\"url\":\"https:\\\/\\\/www.pcb.ub.edu\\\/en\\\/first-observation-of-the-folding-of-a-nucleic-acid\\\/\",\"name\":\"First observation of the folding of a nucleic acid - 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