{"id":110284,"date":"2026-04-21T10:00:20","date_gmt":"2026-04-21T08:00:20","guid":{"rendered":"https:\/\/www.pcb.ub.edu\/inbrain-neuroelectronics-completes-the-first-in-human-study-of-its-brain-computer-interface\/"},"modified":"2026-04-21T11:17:53","modified_gmt":"2026-04-21T09:17:53","slug":"inbrain-neuroelectronics-completes-the-first-in-human-study-of-its-brain-computer-interface","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/inbrain-neuroelectronics-completes-the-first-in-human-study-of-its-brain-computer-interface\/","title":{"rendered":"INBRAIN Neuroelectronics completes the first\u2011in\u2011human study of its brain\u2013computer interface"},"content":{"rendered":"<p><strong><a href=\"https:\/\/www.pcb.ub.edu\/en\/empresa\/inbrain-neuroelectronics-sl\/\" target=\"_blank\" rel=\"noopener\">INBRAIN Neuroelectronics<\/a>, a neurotechnology company developing graphene-based brain-computer interface therapeutics (BCI-Tx), today announced completion of patient recruitment in its first-in-human study evaluating its graphene cortical interface. A total of ten patients were recruited into its first-in-human study, and eight patients were treated surgically, with no perioperative device failure observed during use. Complete datasets were obtained from eight patients.<\/strong><\/p>\n<p>The study (NCT06368310), sponsored by the University of Manchester and conducted in collaboration with the Northern Care Alliance NHS Foundation Trust, evaluated INBRAIN\u2019s graphene cortical interface during neurosurgical procedures for brain tumor resection. The study demonstrated a favorable perioperative safety profile, with no device\u2011related adverse events observed in any of the eight patients treated up to surgical discharge, and included a 90\u2011day post\u2011operative safety follow\u2011up period incorporating imaging assessments.<\/p>\n<p>\u201cThe completion of patient enrollment in this first-in-human study marks an important step for INBRAIN and the field of neurotechnology,\u201d said <strong>Carolina Aguilar<\/strong>, CEO and Co-founder, INBRAIN Neuroelectronics. \u201cGraphene has the potential to fundamentally change how we interface with the brain, enabling higher resolution of neural function specific biomarkers, safer, and more intelligent BCI systems. We look forward to announcing the full results this year, as we advance towards commercialization.\u201d<\/p>\n<p>\u201cThe ability to detect high-frequency neural activity with micrometer-scale precision and also modulate it provides a fundamentally new level of insight into brain\u2013tumor interactions and functional brain decoding and mapping. This level of resolution has the potential to significantly improve surgical precision and open new avenues for treating neurological disorders,\u201d said <strong>Dr. David Coope<\/strong>, Chief Clinical Investigator and Consultant Neurosurgeon at the Manchester Centre for Clinical Neurosciences at Northern Care Alliance and the Geoffrey Jefferson Brain Research Centre.<\/p>\n<p>During brain surgery, graphene electrodes are used to map and monitor neural activity, helping surgeons identify and preserve critical functions such as movement and speech. However, conventional electrodes are limited by their rigidity, size, and signal sensitivity, which can restrict their ability to conform to the brain\u2019s complex surface and capture detailed neural activity.<\/p>\n<p>INBRAIN\u2019s graphene-based electrodes represent a new class of neural interface technology designed to overcome these challenges. Ultra-thin, micrometric and highly flexible, they closely adapt to the brain\u2019s contours and access hard-to-reach areas. By replacing metal contacts with graphene, a highly sensitive carbon-based material, these devices enable higher-resolution signal detection and more precise stimulation, supporting real-time, more detailed brain decoding and mapping during surgery.<\/p>\n<p>\u201cThis study demonstrates that graphene can safely interface with the human brain, and capture neural signals with exceptional fidelity and resolution to enable precise decoding of brain and speech-related patterns metals can barely see,\u201d said <strong>Dr. Kostas Kostarelos<\/strong>, Co-Founder of INBRAIN Neuroelectronics and Chief Scientific Investigator of the study. \u201cIt marks a pivotal step towards translating a new enabling technology using neural signals into meaningful clinical applications and real-world patient benefit.\u201d<\/p>\n<p><strong>\u00bb <a href=\"https:\/\/www.businesswire.com\/news\/home\/20260420000990\/en\/INBRAIN-Neuroelectronics-Completes-Enrolment-of-Worlds-First-in-Human-Study-of-Graphene-Neural-Interfaces-for-Brain-Decoding-Mapping\" target=\"_blank\" rel=\"noopener\">Link to the news [+]<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>INBRAIN Neuroelectronics, a neurotechnology company developing graphene-based brain-computer interface therapeutics (BCI-Tx), today announced completion of patient recruitment in its first-in-human study evaluating its graphene cortical interface. A total of ten&#8230;<\/p>\n","protected":false},"author":14,"featured_media":106216,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[90],"tags":[341],"class_list":["post-110284","post","type-post","status-publish","format-standard","has-post-thumbnail","category-entities","tag-inbrain-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>INBRAIN Neuroelectronics completes the first\u2011in\u2011human study of its brain\u2013computer interface - Parc Cient\u00edfic de Barcelona<\/title>\n<meta name=\"description\" content=\"A total of ten patients were recruited into its first-in-human study, and eight patients were treated surgically.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pcb.ub.edu\/inbrain-neuroelectronics-completa-el-primer-estudi-en-humans-de-la-seva-interficie-cervell-ordinador\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"INBRAIN Neuroelectronics completes the first\u2011in\u2011human study of its brain\u2013computer interface - 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