{"id":109241,"date":"2026-02-25T16:18:23","date_gmt":"2026-02-25T15:18:23","guid":{"rendered":"https:\/\/www.pcb.ub.edu\/the-university-of-barcelona-presents-visi-on-brain-a-training-and-research-network-in-neuroscience-based-on-new-generation-human-models\/"},"modified":"2026-02-25T17:06:27","modified_gmt":"2026-02-25T16:06:27","slug":"the-university-of-barcelona-presents-visi-on-brain-a-training-and-research-network-in-neuroscience-based-on-new-generation-human-models","status":"publish","type":"post","link":"https:\/\/www.pcb.ub.edu\/en\/the-university-of-barcelona-presents-visi-on-brain-a-training-and-research-network-in-neuroscience-based-on-new-generation-human-models\/","title":{"rendered":"The University of Barcelona presents VISI-ON-BRAIN, a training and research network in neuroscience based on new-generation human models"},"content":{"rendered":"<p><strong>The University of Barcelona is consolidating its position at the forefront of European research thanks to the strategic project \u201cVISI-ON-BRAIN: Cutting-edge Human In Vitro and In Silico Biomedical Tools on Brain Disorders\u201d. This is a training and research programme involving 15 PhD researchers focused on developing new-generation human models to advance the study of complex brain disorders such as Alzheimer\u2019s, Parkinson\u2019s and Huntington\u2019s disease. The key point of the initiative is the paradigm shift it proposes, as the study is carried out leaving behind the animal model and seeking a more ethical science, with experimental (in vitro) and computational (in silico) models.<\/strong><\/p>\n<p><strong>Josep M. Canals<\/strong>, professor at the UB\u2019s Faculty of Medicine and Health Sciences, leads this project, which is part of the Horizon Europe programme and has received \u20ac4.5 million in funding under the Marie Sk\u0142odowska-Curie Doctoral Networks (MSCA-DN). <strong>Canals<\/strong> is a member of the UB Institute of Neurosciences (UBneuro) and director of the Production and Validation Center of Advanced Therapies (Creatio), located at the Barcelona Science Park (PCB-UB).<\/p>\n<h3><strong>Neuroscience: new ethical models for studying human biology<\/strong><\/h3>\n<p>The field of biomedical R&amp;D is undergoing a transformation towards scientific innovation without the use of laboratory animals and the promotion of more ethical and effective science for humans. In Europe, this includes a EC roadmap to phase out animal testing, as well as a call from the European Parliament to accelerate the transition with clearer objectives and timelines. In the United States, the Food and Drug Administration (FDA) has outlined a plan to reduce animal testing in preclinical safety studies and to expand new approach methodologies (NAMs), which include advanced computational systems and <em>in vitro<\/em> methods.<\/p>\n<p>Neuroscience makes this transition mission-critical: the development of therapeutic agents to address neurodegeneration has experienced exceptionally high failure rates, underscoring the need to establish models that better reflect human biology and disease progression. The EU\u2019s most ambitious competitive push \u2014 through the \u2018Choose Europe for Life Sciences\u2019 strategy and the European Biotechnology Act \u2014 reinforces this guideline by translating results from the laboratory to the market, boosting innovation uptakes and accelerating the real-world impact of research.<\/p>\n<h3><strong>VISI-ON-BRAIN: a pan-European, cross-sector training and research platform<\/strong><\/h3>\n<p>The programme brings together 15 academic, clinical and industrial partners from eight European countries, a structure that will enable PhD researchers to combine innovation in laboratories with advanced models, analysis and translational validation. The project is coordinated by the UB through Creatio. The beneficiary consortium includes the Technical University of Denmark (Denmark), the Prinses M\u00e1xima Centrum for Paediatric Oncology (Netherlands), the University of T\u00fcbingen (Germany), Lund University (Sweden), Cardiff University and King\u2019s College London (United Kingdom), the National Research Council (Italy), Starlab Barcelona SL (Spain) and FRESCI (Spain). Associate members are the University of Milan-Bicocca (Italy), Utrecht University (Netherlands), VeriGraft (Sweden), San Raffaele Hospital SRL (Italy) and the European Commission\u2019s Joint Research Centre (JRC) (Italy).<\/p>\n<h3><strong>Why is this important? From more data to better evidence<\/strong><\/h3>\n<p>Brain disorders are a major challenge for global health and a substantial societal and economic burden. VISI-ON-BRAIN will accelerate the development of relevant decision-making tools for patient treatment, enabling more go\/no-go decisions, de-risk translation and improving the efficiency of discoveries and therapeutic development. Beyond science, it is an investment in workforce and competitiveness: it is about training doctoral researchers who can move easily between academia, clinical research and industry, and help NAMs, from promising methods to validated practices, always in line with evolving expectations.<\/p>\n<p>In this context, the UB promotes scientific innovation without the use of experimental animals and the promotion of more ethical and effective science for humans, with the creation of the Hub for Alternative Methods to Animal Experimentation, coordinated by Professor <strong>Josep M. Canals<\/strong>.<\/p>\n<p>VISI-ON-BRAIN is funded by the European Union under the Marie Sk\u0142odowska-Curie grant agreement N. 101227124. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them.<\/p>\n<p><strong>\u00bb Access to the news:<\/strong> <a href=\"https:\/\/web.ub.edu\/en\/web\/actualitat\/w\/training-research-network-neuroscience-visi-on-brain?referer=news\" target=\"_blank\" rel=\"noopener\">University of Barcelona website [+]<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The University of Barcelona is consolidating its position at the forefront of European research thanks to the strategic project \u201cVISI-ON-BRAIN: Cutting-edge Human In Vitro and In Silico Biomedical Tools on&#8230;<\/p>\n","protected":false},"author":14,"featured_media":109229,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[36],"tags":[386],"class_list":["post-109241","post","type-post","status-publish","format-standard","has-post-thumbnail","category-science","tag-creatio"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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