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Chemotargets puts computational biotechnology within everyone´s rearch

By 18 de May de 2015November 18th, 2020No Comments
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Chemotargets team (Photo: Daniel Portales, Parc Científic de Barcelona).
 18.05.2015

Chemotargets puts computational biotechnology within everyone´s rearch

Chemotargets –a  IMIM-Hospital del Mar spin off, based at the Parc Científic de Barcelona– has brought to market a new version of its CTlink software, a highly advanced computational package capable of predicting how a small molecule interacts with thousands of proteins. CTlink[GUI] is a software graphical user interface that analyses obtained results in a much more intuitive, interactive and effective manner. With this new innovative platform, the company aims to bring technology closer to users who are not specialists in the computational field.

CTLink, the first product that Chemotargets has brought to market, is an innovative software tool capable to build models predicting the activity of millions of small molecules against thousands of proteins in a highly efficient manner. The software package is designed in a modular way, for any type of computer, and predicts different biological profiles (pharmacology, safety, etc.) of small molecules (pharmaceuticals, cosmetics, agrochemicals or environmental contaminants, etc.). The software is also able to foresee many potential causes of failure in the process of drug discovery. At present, several national and international pharmaceutical companies have already acquired the license.

So far, CTLink was commercially available as a tool based exclusively on the command line and, therefore, aimed only at researchers experienced in computational chemistry and molecular modeling. With the release of CTLink [GUI], CTLink´s graphic interface, Chemotargets aims to bring this innovative platform to non-specialized users, such as medicinal chemists, pharmacologists, toxicologists and other researchers.

“Anyone who wants to know which proteins interact with a small molecule can now use this platform. You just have to draw, or upload the structure of one or more molecules from a file, and send it to the server and the program will provide you with the list of interacting proteins including both experimentally known and newly predicted ones” explains Jordi Mestres, Chemotargets, CEO and coordinator of the Chemogenomics research group at the Biomedical Informatics Program (GRIB) of the IMIM-UPF.

Supporting the growth of translation science

Chemotargets is a computational biotech company focusing on the areas of drug discovery and development. Founded in 2006 by Jordi Mestres, as a spin-off from the Chemogenomics Laboratory under the auspices of the Municipal Institute of Medical Research (IMIM-Hospital del Mar), the company is based at the Parc Cientific de Barcelona.

Chemotargets’ goal is to help the biopharma industry fast-forward the process of bringing new medicines to market, speeding up drug discovery and development programs and making them more cost-efficient. To this end, Chemotargets has designed, and continues developing, an integrated technology platform involving a broad spectrum of cutting-edge computational methodologies. Since 2006, Chemotargets has provided computational drug discovery services to a great number pharmaceutical and biotech companies, both nationwide and internationally.

At present, Chemotargets has several ongoing collaboration agreements with various academic and research institutions from around the world and participates in several research projects funded by the European Union. In recent years, it has taken the strategic decision to diversify its market potential by making scientific software their primary objective of business.

 

For further information: See the tutorial video clip  CTlink[GUI]