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IBEC Seminar: Mechanical control of cell division


During development and adult tissue homeostasis, cellular behavior is controlled by signals that cells receive from their local environment. This is not limited to biochemical signals, as cell behavior can be instructed by mechanical forces exerted by neighbouring cells and the surrounding tissue. Cells sense this mechanical information through numerous molecules, including cell adhesion receptors, which translate mechanical cues into an appropriate cellular response. I will discuss our recent findings on force transduction through the cell-cell adhesion protein E-cadherin, and its central role in the mechanical control of cell division to regulate epithelial integrity and architecture.

Data i hora d'inici: 04/10/2019, 10.00h

Data i hora de fi: 04/10/2019, 12.00h

Organitzador: IBEC - Institute for Bioengineering of Catalonia

Lloc: Edifici Torres R+D+I, TI 11

Host: Xavier Trepat