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Smrcka,
AV; Kichik, N; Tarragó, T; Burroughs, M; Park, MS;
Itoga, NK; Stem, HA; Willardson, BM; Giralt, E
NMR
analysis of G-protein betabamma subunit complexes reveals
a dynamic G(alpha)-G(betagamma) subunit interface and multiple
protein recognition modes
Proc Natl Acad Sci USA (2010) 107, 639-644
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Carulla,
N; Zhou, M; Arimon, M; Gairi, M; Giralt, E; Robinson, C;
Dobson, C M
Experimental
characterization of disordered and ordered aggregates populated
during the process of amyloid fibril formation
PNAS (2009) 106, 7828-7833
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Pellechia,
M; Bertini, I; Cowburn, D; Dalvit, C; Giralt, E; Jahnke,
W; James, TL; Homans, SW; Kessler, H; Luchinat, BM; Oschkinat,
H; Peng, J; Schwalbe, H; Siegal, G
Perspectives
on NMR in drug discovery: a technique comes of age
Nature Reviews Drug Discovery (2008) 7, 738-745
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Gordo,
S; Martos,V; Santos, E; Menéndez, M; Bo, C; Giralt,
E; de Mendoza, J
Stability
and structural recovery of the tetramerization domain of p53-R337H
mutant induced by a designed templating ligand
PNAS (2008) 105, 16426-31
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Teixidó,
M; Zurita, E; Malakoutikhah, M; Tarrago, T; Giralt, E
Diketopiperazines
as a tool for the study of transport acroos the blood-brain
barrier(BBB) an their potential use as BBB-shuttles.
J. Am. Chem. Soc. (2007) 129, 11802-13
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Pujals,
S; Fernández-Carneado, J; Kogan, M; Martínez,
J; Cavelier, F; Giralt, E
Replacement
of a proline with silaproline causes a 20-fold increase in
the cellular uptake of a Pro-rich peptide
J. Am. Chem. Soc. (2006) 128, 8479-8483
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Nicolas,
E; Ferrrer, C; Taboada, L; Giralt, E
Coupe
du roi bisection of proteins. Spontaneous tetramerization
of two peptides that span the sequence of the rabbit uteroglobin
monomer
J. Am. Chem. Soc. (2005) 127, 17719-17733
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Carulla,
N; Caddy, G; Hall, DR; Zurdo, J; Gairí, M; Feliz,
M; Giralt, E; Robinson, CV; Dobson, CM
Molecular
recycling within amyolid fibrils
Nature (London, UK) (2005) 436, 554-558
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Fernández-Carneado,
J; Van Gool, M; Martos, V; Castel, S; Prados, P; de Mendoza,
J; Giralt, E
A
new class of highly efficient, non-peptidic oligoguanidinium
vectors that selectively internalize into mitochondria
J. Am. Chem. Soc. (2005) 127, 869-874
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Farrera-Sinfreu,
J; Giralt, E; Castel, S; Albericio, F; Royo, M
Cell-penetrating
cis-g-amino-L-proline-derived peptides
J. Am. Chem. Soc. (2005) 127, 9459-9468
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Crespo,
L; Sanclimens, G; Pons, M; Giralt, E; Royo, M, Albericio,
F
Peptide
and amide-bond containing dendrimers
Chem. Rev. (2005) 105, 1663-1681
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Farrera-Sinfreu,
J; Zaccaro, L; Vidal, D; Salvatella, X; Giralt, E, Pons,
M; Albericio, F; Royo, M
A
new class of foldamers based on cis-gamma-amino-L-
-proline 1,2
J. Am. Chem. Soc. (2004) 126, 6048-6057
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Fernández-Carneado,
J; Kogan, MJ; Castel, S; Giralt, E
Amphipatic
Pro-rich peptides derived from the N-terminal domain of g-zein
as potential peptide carriers
Angew. Chem. Int. Ed. (2004) 43, 1811-1814
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Salvatella,
X; Martinell, M; Gairí, M; Mateu, MG; Feliz, M; Hamilton,
AD; de Mendoza, J; Giralt, E
A
tetraguanidinium ligand binds to the surface ot the tetramerization
domain of p53
Angew. Chem. Int. Ed. (2004) 43, 196-198