Malignant tumors in flies

We model cancer in flies
to understand the cellular changes that drive malignant growth and
to identify conserved mechanisms that might be relevant for human cancer therapy.
Rossi F, Gonzalez C. (2011). Synergism between altered cortical polarity and the PI3K/TOR pathway in the suppression of tumour growth.
Januschke et al. Drosophila neuroblasts retain the daughter centrosome.
Wang C, et al., (2011). An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts.

We model cancer in flies
to understand the cellular changes that drive malignant growth and
to identify conserved mechanisms that might be relevant for human cancer therapy.