Our research aims at the obtention of small libraries of peptidomimetics and conformationally constrained pseudopeptides by replacement of some amino acids of natural peptides by functionalized 3-aminolactam surrogates.

We are currently developing the following subjects: 

- Inhibitors of HIV-1 protease dimerization

- Mimetics of miraziridine A as cathepsin inhibitors

- Mimetics of melanotan II as anticancer agents

- Mimetics of stylostatin 1 as antibiotics acting on the procariot cell membrane

Group leader

Anna Diez
University Professor
Department of Pharmacology and Medicinal Chemistry

Mario Rubiralta
Full Professor
Department of Pharmacology and Medicinal Chemistry

Montse Cruz
PhD in Chemistry. Researcher

Ana Belén Sánchez
PhD in Pharmacy. Researcher

Xavier del Río
MS in Pharmacy, Ph.D. student

Patricia López
MS in Chemistry, Ph.D student

Eulàlia Pinyol
Degree in Chemistry, Ph.D student

Carlos López
Degree in Pharmacy, Ph.D. student

Jordi Mas
Degree in Pharmacy, Ph.D. student

Collaborations

- Prof. Ernest Giralt (PCB-Universitat de Barcelona)
- Prof. Mathias Winterhalter (International University of Bremen, Germany)
- Prof. José A. Esté (Hospital Trias i Pujol, Barcelona)

- Pharmamar, S.A.
- Laboratoris Esteve, S.A.

Other recent collaborations

- Prof. Henri-Philippe Husson (University of Paris V, France)
- Dr. Laurent Micouin (CNRS, University of Paris V, France)
- Dra. Martine Bonin (CNRS, University of Paris V, France)
- Prof. Jean-Claude Teulade (Univ. of Auvergne, Clermont-Ferrand, France)
- Prof. Javier Luque (Universitat de Barcelona)

- Almirall-Prodesfarma, S.A.

Available positions

Masters, Ph.D., and Post-Doc.

Related Links

Xarxa de Química Mèdica
http://www.ub.edu/farmaco/orgchem/english/index.htm